38750-01-5

Upstream product

• 564472-38-4 3-(4-methyl-2-pentenoyl)-2-oxazolidinone 
• 1061567-18-7 C₁₃H₁₇NO₄ 
• 187986-27-2 (1R,2S,6R,8R,10R,11S)-11-isopropyl-10-methoxy-6-methyl-5-methylene-9-oxatricyclo[6.2.1.0^2,6]undecan-7-one 
• 187986-28-3 (1S,2S,6R,8R,10R,11S)-10-(3-chloroperoxybenzoyl)-11-isopropyl-6-methyl-5-methylene-9-oxatricyclo[6.2.1.0^2,6]undecan-7-one 
• 187986-19-2 (1R,2S,6R,8R,10R,11S)-11-Isopropyl-10-methoxy-6-methyl-5-[1-trimethylsilanyl-meth-(Z)-ylidene]-9-oxa-tricyclo[6.2.1.0^2,6]undecan-7-one 
• 187986-24-9 (1R,5R,7S,8S)-8-isopropyl-7-methoxy-3-methyl-6-oxabicyclo[3.2.1]oct-2-en-4-one 
• 187986-21-6 (1R,5R,7R,8S)-8-isopropyl-7-methoxy-3-methyl-6-oxabicyclo[3.2.1]oct-2-en-4-one 
• 187986-25-0 (1R,2S,5R,7R,8S)-8-Isopropyl-7-methoxy-3-methyl-2-(4-trimethylsilanyl-but-3-ynyl)-4-trimethylsilanyloxy-6-oxa-bicyclo[3.2.1]oct-3-ene 
• 187986-20-5 (1S,2S,5R,7R,8S)-3-Iodo-8-isopropyl-7-methoxy-3-methyl-2-(4-trimethylsilanyl-but-3-ynyl)-6-oxa-bicyclo[3.2.1]octan-4-one 
• 187986-23-8 (4R,5S,6R)-4-Dimethoxymethyl-5-isopropyl-2-methyl-6-trimethylsilanyloxy-cyclohex-2-enone 

Downstream Products

• 7668-77-1 Dendroxin 
• 2115-91-5 dendrobine 

Relevant academic research and scientific papers

Catalytic Enantioselective Total Synthesis of the Picrotoxane Alkaloids (-)-Dendrobine, (-)-Mubironine B, and (-)-Dendroxine

A concise enantioselective total synthesis of three sesquiterpenoid alkaloids - (-)-dendrobine, (-)-mubironine B, and (-)-dendroxine - is presented, which highlights the state-of-art catalytic methods, including enantioselective Diels-Alder cycloaddition, iron-catalyzed aerobic lactonization, copper-catalyzed cycloisomerization, and free-radical-initiated hydroazidation.

Total synthesis of (-)-dendrobine via α-carbonyl radical cyclization

An efficient total synthesis of enantiomerically pure (-)-dendrobine (1) is accomplished based on an α-carbonyl radical cyclization reaction. (S)- carvotanacetone (6) was convened to bicyclic acetal-enone 4 in five steps. Cul-mediated conjugate addition o