388121-68-4

Usage

Uses

Used in Pharmaceutical Industry:
(4-Amino-3-iodo-phenyl)-methanol is used as an intermediate in the synthesis of various drugs for its ability to contribute to the development of biologically active molecules and pharmaceuticals.
Used in Agrochemical Industry:
(4-Amino-3-iodo-phenyl)-methanol is used as an intermediate in the synthesis of pesticides, playing a crucial role in the creation of effective agrochemical products.
Used in Organic Synthesis:
(4-Amino-3-iodo-phenyl)-methanol is used as a building block for the preparation of diverse organic compounds, highlighting its utility in synthetic chemistry and the development of new chemical entities.

Upstream product

• 94-09-7 p-aminoethylbenzoate 
• 623-04-1 4-aminobenzenemethanol 
• 19718-49-1 4-amino-3-iodobenzoic acid methyl ester 
• 62875-84-7 3-iodobenzocaine 

Downstream Products

• 1233878-35-7 2-((tert-butyldimethylsilyl)oxy)ethyl 3-(2-amino-5-(hydroxymethyl)phenyl)acrylate 
• 167868-43-1 4-azido-3-iodobenzyl alcohol 
• 1606176-67-3 3-((4-amino-3-iodobenzyl)oxy)propanenitrile 

Relevant academic research and scientific papers

Disassembly of polymeric nanoparticles with enzyme-triggered polymer unzipping: Polyelectrolyte complexes: Vs. amphiphilic nanoassemblies

Alkaline phosphatase (ALP) responsive polymers, which can unzip from head to tail are reported. Hydrophilic and hydrophobic modification of the polymer was carried out for the formation of a polyelectrolyte complex and an amphiphilic nanoassembly, respect

Programmable microcapsules from self-immolative polymers

For the autonomous repair of damaged materials, microcapsules are needed that release their contents in response to a variety of physical and chemical phenomena, not just by direct mechanical rupture. Herein we report a general route to programmable microcapsules. This method creates core-shell microcapsules with polymeric shell walls composed of self-immolative polymer networks. The polymers in these networks undergo a head-to-tail depolymerization upon removal of the triggering end group, leading to breakdown of the shell wall and subsequent release of the capsule's liquid interior. We report microcapsules with shell walls bearing both Boc and Fmoc triggering groups. The capsules release their contents only under conditions known to remove these triggering groups; otherwise, they retain their contents under a variety of conditions. In support of the proposed release mechanism, the capsule shell walls were observed to undergo physical cracking upon exposure to the triggering conditions.

Design, synthesis, and in vitro pharmacology of new radiolabeled γ-hydroxybutyric acid analogues including photolabile analogues with irreversible binding to the high-affinity γ-hydroxybutyric acid binding sites

γ-Hydroxybutyric acid (GHB) is a psychotropic compound endogenous to the brain. Despite its potential physiological significance, the complete molecular mechanisms of action remain unexplained. To facilitate the isolation and identification of the high-affinity GHB binding site, we herein report the design and synthesis of the first 125I-labeled radioligands in the field, one of which contains a photoaffinity label which enables it to bind irreversibly to the high-affinity GHB binding sites.

SELF-IMMOLATIVE POLYMERS

Self-immolative polymers, designed to release a chemical moiety, or a plurality of chemical moieties, upon a pre-determined cleavage event, or sequences of events, are disclosed. The polymers can be simple polymers, comb polymers or branched polymers. Fur

HYDRAZONE DERIVATIVE

A compound represented by the following formula (I): wherein R1 represents hydrogen, aryl which may have a substituent, a saturated or unsaturated 5- to 7-membered heterocyclic group which may have a substituent, etc.; R2 represents hydrogen, aryl which may have a substituent, a saturated or unsaturated 5- to 7-membered heterocyclic group which may have a substituent, etc.; R3 represents hydrogen, etc.; Ar represents a divalent group derived from aromatic hydrocarbon, etc.; X represents a single bond, linear or branched alkylene having from 1 to 3 carbon atoms which may have a substituent, etc.; and G represents halogen, a saturated or unsaturated 5- or 6-membered cyclic hydrocarbon group which may have a substituent, a saturated or unsaturated 5- to 7-membered heterocyclic group which may have a substituent, etc., a salt thereof or a solvate thereof; and an agent for inhibiting aggregation and/or deposition of an amyloid protein or an amyloid-like protein, which comprises the compound, a salt thereof or a solvate thereof

Substituted quinolinecarboxamides as antiviral agents

The present invention discloses disubstiuted 4-oxo-1,4-dihydro-3-quinolinecarboxamide derivatives. The compounds are useful as antiviral agents, in particular, as agents against viruses of the herpes family.

Pyrroloquinolones as antiviral agents

The present invention provides a compound of formula I which is useful as antiviral agents, in particular, as agents against viruses of the herpes family.