388121-68-4

Basic information

• Product Name: (4-Amino-3-iodo-phenyl)-methanol
• Synonyms: (4-Amino-3-iodo-phenyl)-methanol
• CAS NO: 388121-68-4
• Molecular Formula: C₇H₈INO
• Molecular Weight: 249.04899
• Mol File: 388121-68-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 346.9±37.0 °C(Predicted)
• Appearance: /
• Density: 1.951±0.06 g/cm3(Predicted)
• PKA: 13.95±0.10(Predicted)
• CAS DataBase Reference: (4-Amino-3-iodo-phenyl)-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Amino-3-iodo-phenyl)-methanol(388121-68-4)
• EPA Substance Registry System: (4-Amino-3-iodo-phenyl)-methanol(388121-68-4)

Safety Data

• Hazardous Substances Data: 388121-68-4(Hazardous Substances Data)

Usage

General Description

(4-Amino-3-iodo-phenyl)-methanol, also known as 3-Iodo-4-aminophenyl methanol, is a chemical compound with the molecular formula C7H8INO. It is a white crystalline solid that is commonly used as a reagent in organic synthesis. (4-Amino-3-iodo-phenyl)-methanol is known for its versatile applications in the pharmaceutical and agrochemical industries, where it is used as an intermediate in the synthesis of various drugs and pesticides. Additionally, it can be used as a building block for the preparation of diverse organic compounds, making it a valuable tool in synthetic chemistry. Due to its strong nucleophilic properties and the presence of an iodo group, (4-Amino-3-iodo-phenyl)-methanol is a useful reagent in the development of biologically active molecules and pharmaceuticals.

Upstream product

• 94-09-7 p-aminoethylbenzoate 
• 623-04-1 4-aminobenzenemethanol 
• 62875-84-7 3-iodobenzocaine 
• 19718-49-1 4-amino-3-iodobenzoic acid methyl ester 

Downstream Products

• 1233878-35-7 2-((tert-butyldimethylsilyl)oxy)ethyl 3-(2-amino-5-(hydroxymethyl)phenyl)acrylate 
• 1606176-67-3 3-((4-amino-3-iodobenzyl)oxy)propanenitrile 
• 167868-43-1 4-azido-3-iodobenzyl alcohol 

Relevant articles and documents

Disassembly of polymeric nanoparticles with enzyme-triggered polymer unzipping: Polyelectrolyte complexes: Vs. amphiphilic nanoassemblies

Alkaline phosphatase (ALP) responsive polymers, which can unzip from head to tail are reported. Hydrophilic and hydrophobic modification of the polymer was carried out for the formation of a polyelectrolyte complex and an amphiphilic nanoassembly, respect

Programmable microcapsules from self-immolative polymers

For the autonomous repair of damaged materials, microcapsules are needed that release their contents in response to a variety of physical and chemical phenomena, not just by direct mechanical rupture. Herein we report a general route to programmable microcapsules. This method creates core-shell microcapsules with polymeric shell walls composed of self-immolative polymer networks. The polymers in these networks undergo a head-to-tail depolymerization upon removal of the triggering end group, leading to breakdown of the shell wall and subsequent release of the capsule's liquid interior. We report microcapsules with shell walls bearing both Boc and Fmoc triggering groups. The capsules release their contents only under conditions known to remove these triggering groups; otherwise, they retain their contents under a variety of conditions. In support of the proposed release mechanism, the capsule shell walls were observed to undergo physical cracking upon exposure to the triggering conditions.

SELF-IMMOLATIVE POLYMERS

Self-immolative polymers, designed to release a chemical moiety, or a plurality of chemical moieties, upon a pre-determined cleavage event, or sequences of events, are disclosed. The polymers can be simple polymers, comb polymers or branched polymers. Fur