36940-99-5

Upstream product

• 38841-95-1 1-(p-methoxyphenyl)-4-phenylbutane 
• 18496-54-3 phenylbutyric acid chloride 
• 1821-12-1 4-Phenylbutyric acid 
• 100-66-3 methoxybenzene 
• 101594-58-5 1-(4-methoxyphenyl)-4-phenylbutan-1-one 

Downstream Products

• 113795-34-9 1-(4-Bromo-butoxy)-4-(4-phenyl-butyl)-benzene 
• 113795-13-4 ethyl 2-<4-(4-phenylbutyl)phenoxy>isobutyrate 
• 113795-35-0 1-(5-Bromo-pentyloxy)-4-(4-phenyl-butyl)-benzene 
• 113795-36-1 1-(6-Bromo-hexyloxy)-4-(4-phenyl-butyl)-benzene 
• 113795-38-3 1-(8-Bromo-octyloxy)-4-(4-phenyl-butyl)-benzene 
• 113810-77-8 1-(9-Bromo-nonyloxy)-4-(4-phenyl-butyl)-benzene 
• 100-42-5 styrene 
• 300-57-2 allylbenzene 
• 637-50-3 1-phenylpropene 
• 100-41-4 ethylbenzene 
• 108-88-3 toluene 
• 98-83-9 isopropenylbenzene 
• 113795-30-5 1-(3-Bromo-propoxy)-4-(4-phenyl-butyl)-benzene 
• 113795-27-0 5-Methyl-4-oxy-pyrazine-2-carboxylic acid 2,2-dimethyl-6-[4-(4-phenyl-butyl)-phenoxy]-hexyl ester 

Relevant academic research and scientific papers

EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS

The present invention provides novel compounds that affect excitatory amino acid receptors and are useful in the treatment of neurological disorders. This invention also provides synthetic methods for the preparation of the novel compounds.

Synthesis and Hypolipidemic Activity of 2-Substituted Isobutyric Acid Derivatives

A series of 2-substituted isobutyric acid derivatives have been synthesized and evaluated as hypolipidemic agents.Compounds 11 and 20 were found to decrease the level of plasma total cholesterol in experimental hyperlipidemic rats to a greater extent than clofibrate (CF) and to increase the level of plasma high-density lipoprotein cholesterol to the same extent as gemfibrozil (GF).Increase in liver weight caused by these compounds were less than those with CF and GF.