389873-56-7

Upstream product

• 1779-49-3 Methyltriphenylphosphonium bromide 
• 162052-68-8 3'-O-tert-Butyldimethylsilyl-5'-O-tert-butyldiphenylsilyl-4'-formyl-thymidin 

Downstream Products

• 607716-77-8 1-[5-(tert-butyl-diphenyl-silanyloxymethyl)-4-hydroxy-5-vinyl-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 
• 607716-85-8 C₆₀H₇₂N₅O₁₂PSi₂ 
• 591754-20-0 5'-O-(4,4'-dimethoxysilyl)-4'-C-(ethyl)thymidine 

Relevant academic research and scientific papers

Dna polymerase selectivity: Sugar interactions monitored with high-fidelity nucleotides

Do enzyme - sugar interactions contribute to DNA-polymerase fidelity? With the novel chemical probes 1 (R=CH3)2), which are used by a DNA polymerase more selectively than the natural counterpart (R=H), insights are obtained into the

Substrates for investigation of DNA polymerase function: Synthesis and properties of 4′-C-alkylated oligonucleotides

In addition to their potential as diagnostic and therapeutic agents, modified oligonucleotides have also been shown to be highly valuable tools for examination of complex biological processes. Carefully designed nucleotide analogues have therefore found c

Dinucleotides of 4′-C-vinyl- and 5′-C-allylthymidine as substrates for ring-closing metathesis reactions

Thymidine derivatives containing a 4′-C-vinyl group or a 5′-C-allyl group are synthesized and used as building blocks for three different dinucleotides. These are evaluated as substrates for ring-closing metathesis cyclisations, and a protected 5′-C-allyl