391-83-3Relevant articles and documents
3,6-DISUBSTITUTED-2-PYRIDINALDOXIME SCAFFOLDS
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Paragraph 0095; 0142-0143, (2020/08/27)
The present invention relates to a compound of formula (I), or one of its pharmaceutically acceptable salts: wherein R1, R2 and -X-Y- have specific definitions. It also relates to the use of such a compound as reactivator of acetylcholinesterase for treating organophosphorous nerve agents poisoning; and to a process for preparing it.
Inhibitor IDO and application thereof (by machine translation)
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Paragraph 0139; 0147-0149, (2019/12/09)
The invention belongs to the technical field of medicines, and (I) particularly relates to a compound or a pharmaceutically acceptable salt, an ester, a stereoisomer, a tautomer, a ring A, a B ring R, a ring, and a ring of the compound shown in formula (I
With anti-tumor activity of chlorine oxygen kui derivatives
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, (2017/12/28)
The invention relates to a chloroxoquinoline derivatives with anti-tumor activity and specifically relates to compounds of a formula I as shown in the specification and pharmaceutically acceptable salts, solvates and prodrugs thereof, wherein R1 is selected from hydrogen, -C1-6 alkyl, -C2-6 alkenyl, -C2-6 alkynyl and -C1-6 alkyl-phenyl, and the alkyl, the alkenyl, the alkynyl and the phenyl can be optionally substituted by halogens, nitryl, cyan, hydroxyl, -C1-6 alkoxy and phenyl; R3 is selected from hydrogen, -CONHR31 and -COOR32, the R31 and the R32 are independently selected from -C1-6 alkyl and -C1-6 alkylamino, respectively, and the amino can be optionally substituted by 1 to 2 -C1-6 alkyls; R7 is selected from halogens, -C1-6 alkoxy, morpholinyl and piperazine; the formula I is as shown in the specification.
