39143-08-3

Upstream product

• 19735-89-8 3-methyl-1-phenylpyrazolin-5(4H)-one 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 141-97-9 ethyl acetoacetate 
• 100-63-0 phenylhydrazine 
• 942-32-5 5-methyl-2-phenyl-2H-pyrazol-3-ol 
• 89-25-8 edaravone 

Downstream Products

• 69157-82-0 (4-dimethylamino-phenyl)-(3-methyl-5-oxo-1-phenyl-1,5-dihydro-pyrazol-4-ylidene)-acetonitrile 
• 71237-21-3 [4-(4-dimethylamino-phenyl)-3,5-dimethyl-1-phenyl-1,4-dihydro-pyrano[2,3-c]pyrazol-6-yl]-diethyl-amine 
• 120031-33-6 (5R,10R)-10-(4-Dimethylamino-phenyl)-4,7,8-trimethyl-2-phenyl-2,3-diaza-spiro[4.5]deca-3,7-dien-1-one 
• 120031-33-6 (5R,10S)-10-(4-Dimethylamino-phenyl)-4,7,8-trimethyl-2-phenyl-2,3-diaza-spiro[4.5]deca-3,7-dien-1-one 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 89-25-8 edaravone 

Relevant academic research and scientific papers

An SiO2/ZnBr2 mediated expeditious approach to 3-methyl-1-phenyl-1H-pyrazol-5(4H)-one derivatives in water under microwave irradiation

A new one-pot three-component green approach has been developed for the synthesis of a series of pyrazolone derivatives 2(a-s) from differently substituted aromatic aldehydes, ethylacetoacetate and phenylhydrazine/2,4-dinitrophenylhydrazine in excellent y

Clay Catalysis: Dry Condensation of 3-Methyl-1-phenyl-5-pyrazolone with Aldehydes under Microwave Irradiation

3-Methyl-1-phenyl-5-pyrazolone (1) and arylcarboxyaldehydes (2) were condensated to 1-phenyl-3-methyl-4-(arylmethylene)-5-pyrazolone (3) in presence of acidic clay KSF without solvent under microwave irradiation.

Investigations on the Hydrolytic Stability of 4-Arylmethylidene-2-pyrazolin-5-ones

The 4-Arylmethylidene-2-pyrazoline-5-ones S are not stable under aqueous alkaline conditions.By the substitution of R3 with electron donor substituents S reacts preferably yielding aldehyde A and 2-pyrazoline-5-one P, while with electron acceptor substituents S forms 4,4'-arylmethylidene-bis-2-pyrazoline-5-one B.The intermediate of hydrolysis is 4-(arylhydroxymethyl)-2-pyrazoline-5-one SOH.The second order rate constants of the reactions of S with hydroxidions and with 2-pyrazoline-5-ones P(-) are determined.The dependence of the hydrolytic decomposition of S on the pH value, substituents and temperature is suitable for the intermediate formation of SOH.