39145-48-7

Usage

Type of compound

Synthetic organic compound

Usage

Herbicide

Physical state at room temperature

White crystalline solid

Solubility in water

Insoluble

Solubility in organic solvents

Soluble

Environmental impact

Toxic to aquatic life, potential environmental pollutant

Banned in many countries

Yes

Harmful effects on human health

Potential to cause liver and kidney damage

Environmental concerns

Suspected carcinogen, persistence in soil and water for long periods of time, concerning environmental contaminant

InChI:InChI=1/C12H7Cl2NO3/c13-8-1-6-11(14)12(7-8)18-10-4-2-9(3-5-10)15(16)17/h1-7H

Upstream product

• 583-78-8 2,5-dichlorophenol 
• 100-00-5 4-chlorobenzonitrile 
• 350-46-9 4-Fluoronitrobenzene 

Downstream Products

• 61575-24-4 4-(2,5-dichlorophenoxy)aniline 
• 1596271-91-8 (E)-2-(4-chlorophenyl)-1-(4-(7-chloroquinolin-4-ylamino)butyl)-3-(4-(2,5-dichlorophenoxy)phenyl)guanidine 
• 1596271-90-7 (E)-2-(4-chlorophenyl)-1-(3-(7-chloroquinolin-4-ylamino)propyl)-3-(4-(2,5-dichlorophenoxy)phenyl)guanidine 
• 1596271-87-2 (E)-2-(4-chlorophenyl)-1-(2-(7-chloroquinolin-4-ylamino)ethyl)-3-(4-(2,5-dichlorophenoxy)phenyl)guanidine 
• 1596271-84-9 (E)-2-(3-chlorophenyl)-1-(4-(7-chloroquinolin-4-ylamino)butyl)-3-(4-(2,5-dichlorophenoxy)phenyl)guanidine 
• 1596271-81-6 (E)-2-(3-chlorophenyl)-1-(3-(7-chloroquinolin-4-ylamino)propyl)-3-(4-(2,5-dichlorophenoxy)phenyl)guanidine 
• 1596271-79-2 (E)-2-(3-chlorophenyl)-1-(2-(7-chloroquinolin-4-ylamino)ethyl)-3-(4-(2,5-dichlorophenoxy)phenyl)guanidine 
• 1596271-77-0 (E)-1-(4-(7-chloroquinolin-4-ylamino)butyl)-3-(4-(2,5-dichlorophenoxy)phenyl)-2-phenylguanidine 
• 1596271-75-8 (E)-1-(3-(7-chloroquinolin-4-ylamino)propyl)-3-(4-(2,5-dichlorophenoxy)phenyl)-2-phenylguanidine 
• 1596271-73-6 (E)-1-(2-(7-chloroquinolin-4-ylamino)ethyl)-3-(4-(2,5-dichlorophenoxy)phenyl)-2-phenylguanidine 
• 1596271-25-8 1-(4-chlorophenyl)-3-(4-(2,5-dichlorophenoxy)phenyl)thiourea 
• 1596271-23-6 1-(3-chlorophenyl)-3-(4-(2,5-dichlorophenoxy)phenyl)thiourea 
• 1596271-22-5 1-(4-(2,5-dichlorophenoxy)phenyl)-3-phenylthiourea 
• 2688-84-8 2-phenoxyaniline 

Relevant academic research and scientific papers

AGRICULTURAL CHEMICALS

The present invention relates to picolinic acid derivatives that are useful in treating fungal diseases ofplants.

Synthesis and evaluation of new diaryl ether and quinoline hybrids as potential antiplasmodial and antimicrobial agents

Synthesis and bioevaluation of new diaryl ether hybridized quinoline derivatives as antiplasmodial, antibacterial and antifungal agents is reported. It was encouraging to discover that several compounds displayed 2-3 folds better efficacy than chloroquine in chloroquine-resistant K1 strain of Plasmodium falciparum. Further, a few members of the library displayed good antibacterial efficacy against gram positive strains of bacteria but none of the compounds displayed any significant antifungal activity.

COMPOUNDS AND METHODS FOR PKC THETA INHIBITION

The present invention provides a method of selectively inhibiting PKC in the presence of PKC, by administering to a subject in need thereof, a therapeutically effective amount of a compound of Formula I. The present invention also provides a method of inhibiting cytokine synthesis in a T cell, a method of inhibiting T cell proliferation, and a method of inhibiting the replication of and cytokine production by T lymphocytes, while not stimulating or inhibiting the replication of B lymphocytes.

3-Amino-4-carboalkoxy-benzoic acid 4'-phenoxy-anilides

3-Amino-4-lower carboalkoxy-benzoic acid-4'-phenoxy-anilides which may be halogenated in the phenoxy nucleus are obtained by reacting the corresponding 4-carboalkoxy-benzoyl chlorides having in 3-position a group capable of yielding the amino group with a 4-amino-diphenyl ether which may be halogenated in the phenyl nucleus which is not substituted by the amino group, and setting free the amino group from the group capable of yielding it. The products are diazo components for azo pigments, especially of the 2-hydroxy-3-naphthoic acid arylide type.