3916-80-1Relevant academic research and scientific papers
Experimental and DFT studies on competitive heterocyclic rearrangements. Part 2: A one-atom side-chain versus the classic three-atom side-chain (Boulton-Katritzky) ring rearrangement of 3-acylamino-1,2,4-oxadiazoles
Pace, Andrea,Pibiri, Ivana,Piccionello, Antonio Palumbo,Buscemi, Silvestre,Vivona, Nicolo,Barone, Giampaolo
, p. 7656 - 7666 (2007)
(Chemical Equation Presented) The experimental investigation of the base-catalyzed rearrangements of 3-acylamino-1,2,4-oxadiazoles evidenced a new reaction pathway which competes with the well-known ring-degenerate Boulton-Katritzky rearrangement (BKR). T
A Highly Efficient Diversification of 2-Amino/Amido-1,3,4-oxadiazole and 1,3,4-Thiadiazole Derivatives via Reagent-Based Cyclization of Thiosemicarbazide Intermediate on Solid-Phase
Yang, Seung-Ju,Choe, Ji-Hye,Abdildinova, Aizhan,Gong, Young-Dae
, p. 732 - 741 (2015/12/23)
A 2-amino/amido-1,3,4-oxadiazole and 1,3,4-thiadiazole library has been constructed on solid-phase organic synthesis. The key step on this solid-phase synthesis involves the preparation of polymer-bound 2-amino-1,3,4-oxadiazole and 1,3,4-thiadiazole core
Influence of solvent from which crystals of 2-amino-5-aryl-1,3,4-oxadiazoles grow on acetylation reaction in solid state
Dymshits,Rublewa
, p. 255 - 260 (2007/10/03)
The phenomenon of reaction anisotropy, i.e. forming of different products on different crystals' facets, is characteristic for 2-amino-5-aryl-1,3,4-oxadiazoles solid-state acetylation. In this case, the ratio of products in reaction yield depends on the f
SOLID-PHASE ACYLATION OF 2-AMINO-5-ARYL-1,3,4-OXADIAZOLES I. THE DUAL REACTIVITY OF CRYSTALLINE 2-AMINO-5-ARYL-1,3,4-OXADIAZOLES DURING ACYLATION BY ACETYL BROMIDE VAPOR
Rubleva, O. G.,Dymshits, V. A.,Ginak, A. I.,Apter, Yu. M.
, p. 1391 - 1394 (2007/10/02)
During the solid-phase acylation of 2-amino-5-aryl-1,3,4-oxadiazoles by acetyl bromide vapor, in contrast to homogeneous acylation, four reaction products are formed.They include the products from acylation at the amino group and acylation of the nitrogen atom of the heterocycle.
