39198-81-7Relevant academic research and scientific papers
Colloidal and Nanosized Catalysts in Organic Synthesis: XXIII. Reductive Amination of Carbonyl Compounds Catalyzed by Nickel Nanoparticles in a Plug-Flow Reactor
Mokhov, V. M.,Nebykov, D. N.,Paputina, A. N.,Popov, Yu. V.,Shishkin, E. V.
, p. 2333 - 2340 (2020/02/25)
Reductive amination of aldehydes and ketones with primary and secondary amines under catalysis with nickel nanoparticles supported on zeolite X, MgO, or activated carbon in the gas phase or in the gas-liquid system in a plug-flow reactor proceeds at atmospheric pressure of hydrogen with the formation of secondary or tertiary amines in high yield.
Colloidal and Nanosized Catalysts in Organic Synthesis: XX. Continuous Hydrogenation of Imines and Enamines Catalyzed by Nickel Nanoparticles
Popov, Yu. V.,Mokhov,Latyshova,Nebykov,Panov,Davydova
, p. 2035 - 2038 (2018/12/11)
Nickel nanoparticles on the BAU-A active carbon or NaX zeolite catalyze hydrogenation of imines and enamines in a flow reactor in a gas phase or in a gas–liquid–solid catalyst system. The process occurs at atmospheric pressure of hydrogen and gives secondary or tertiary amines in a high yield.
Colloid and nanosized catalysts in organic synthesis: XVII. Reductive amination of carbonitriles in the presence of supported nickel nanoparticles
Popov, Yu. V.,Mokhov,Latyshova,Panov,Shirkhanyan
, p. 2546 - 2551 (2017/12/26)
Reductive amination of carbonitriles catalyzed by nickel nanoparticles applied onto a solid support in a plug flow reactor in the gas phase or the gas–liquid–solid catalyst system occurs at atmospheric pressure of hydrogen affording the nonsymmetrical secondary or tertiary amines. The effect of the support type on the target product yield and conversion of the substrate has been studied.
Catalytic hydrogenation of amides to amines under mild conditions
Stein, Mario,Breit, Bernhard
supporting information, p. 2231 - 2234 (2013/03/28)
Under (not so much) pressure: A general method for the hydrogenation of tertiary and secondary amides to amines with excellent selectivity using a bimetallic Pd-Re catalyst has been developed. The reaction proceeds under low pressure and comparatively low temperature. This method provides organic chemists with a simple and reliable tool for the synthesis of amines. Copyright
Aminomethylation of organic halides promoted by zinc in protic medium
Estevam, Idália H. S.,Da Silva, Margarete F.,Bieber, Lothar W.
, p. 7601 - 7604 (2007/10/03)
Organic halides undergo smooth aminomethylation by secondary amines and aqueous formaldehyde promoted by metallic zinc under copper(I) catalysis. Good to excellent yields are obtained with primary, secondary, and tertiary iodides, allylic, propargylic, and benzylic bromides and with α-bromoesters. In most cases, DMSO is the best solvent, but dioxane is preferable for some more reactive halides. Additional experiments with radical quenchers and promoters and the use of 'radical clocks' indicate a stepwise reaction mechanism initiated by the attack of an alkyl radical to iminium ion.
A novel aminomethylation reaction of gaseous alkanes with tert-methylamine N-oxides via C-H bond activation by copper(II) salts
Taniguchi, Yuki,Horie, Shiro,Takaki, Ken,Fujiwara, Yuzo
, p. 137 - 142 (2007/10/03)
The Cu(OAc)2/CF3COOH (TFA) system catalyzes the aminomethylation of gaseous alkanes such as propane and ethane with trimethylamine N-oxide to give N,N-dimethylisobutylamine (1) and N,N-dimethylpropylamine (7), respectively.The corresponding trifluoroacetates are also formed as by-products from the reactions of methane and propane. Keywords: Copper acetate; Aminomethylation; Amine N-oxide; C-H bond activation; C-C bond formation; Alkane
Formic Acid Reduction of Enamines. Scope of the Reaction
Nilsson, Asa,Carlson, Rolf
, p. 187 - 190 (2007/10/02)
The scope of enamine reduction with formic acid has been investigated.The compounds studied include enamines from aldehydes, aliphatic ketones, aryl alkyl ketones and functionalized ketones.The procedure is simple and allows the reaction to be conducted without solvent.The method gives short reaction times and generally good yields of saturated amines.
Scope and Pathway of Catalytic Aminomethylation of Olefins
Jachimowicz, Felek,Raksis, Joseph W.
, p. 445 - 447 (2007/10/02)
We describe a general and high-yield one-step process for synthesis of tertiary and secondary amines from olefins, carbon monoxide, water, and a nitrogen source in the presence of transition-metal compounds as catalysts.We find this chemistry, initially d
