392686-87-2

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 110-60-1 1,4-diaminobutane 
• 105-13-5 4-Methoxybenzyl alcohol 

Downstream Products

• 218956-13-9 N₁,N₄-bis(4-methoxybenzyl)butane-1,4-diamine 
• 91122-64-4 3-[4-(4-Oxo-2-phenyl-thiazolidin-3-yl)-butyl]-2-phenyl-5-[1-phenyl-meth-(Z)-ylidene]-thiazolidin-4-one 
• 91122-56-4 C₂₄H₂₈N₂O₄S₂ 

Relevant academic research and scientific papers

Molybdenum-catalyzed diastereoselective anti-dihydroxylation of secondary allylic alcohols

In this protocol, we report a Mo-catalyzed anti-dihydroxylation of secondary allylic alcohols, providing a general method for the preparation of 1,2,3-triols bearing up to three continuous stereocenters with excellent diastereocontrol. The mechanistic studies reveal that this dihydroxylation reaction consists of two steps and up to excellent diastereomeric ratios of the final triol products can be achieved due to the high level of both diastereocontrol in the initial epoxidation and regiocontrol in the following hydrolysis in situ.

A minimalistic approach to develop new anti-apicomplexa polyamines analogs

The development of new chemical entities against the major diseases caused by parasites is highly desired. A library of thirty diamines analogs following a minimalist approach and supported by chemoinformatics tools have been prepared and evaluated agains

Aerobic oxidative coupling of alcohols and amines towards imine formation by a dicopper(I,I) catalyst

A dicopper(I,I) complex [Cu2(L1) (Cl)2] (1), bearing a Cu2Cl2 core spanned by a naphthyridine–diimine ligand is synthesized by the treatment of CuCl with 2,7–bis(N–mesitylmethylimino)–1,8–naphthyridine (L1). The catalytic efficacy of 1 is assessed for aerobic oxidative synthesis of imines from alcohols and amines. The title complex is found to be an excellent catalyst for a wide variety of alcohols and amines. Kinetic experiments revealed the involvement of both copper ions in the aerobic oxidation process. The general utility of naphthyridine based ligands to favour a possible bimetallic pathway for a catalytic reaction is demonstrated here.

Synthesis and antikinetoplastid activity of a series of N,N×-substituted diamines

A series of 25 N,N×-substituted diamines were prepared by controlled reductive amination of free aliphatic diamines with different substituted benzaldehydes. The library was screened in vitro for antiparasitic activity on the causative agents of human Afr

Synthesis of imines, diimines and macrocyclic diimines as possible ligands, in aqueous solution

Although it is recognized that the presence of water is disadvantageous for imine synthesis, we demonstrate that such synthesis can be effective in completely aqueous media, without any catalyst and under mild conditions. Thus, arylaryl, aryl-alkyl, alkyl-aryl and alkyl-alkyl monoimines as well as a large variety of diimines are obtained by direct condensation of the corresponding carbonyl compounds and amines, in water. The same process is used to synthesize macrocyclic diimines starting from methylene, ethylene, trimethylene and tetramethylene glycol bis(2-formylphenyl ether) and ethylene-, trimethylene- and tetramethylene-diamine, some of these macrocycles being known for their chelating properties.

Studies on Thiazolidinones. Part-XIV: Synthesis of 3,3'-Bisthiazolidinones and 2,2-Disubstituted Thiazolidinones from Azomethines

Several new 3,3'-bisthiazolidinones (III) and 2,2-disubstituted thiazolidinones (VIII) have been synthesised by the cycloadditive dehydration of thioglycolic acid to the azomethin derivatives (II) and (VII) prepared from the aliphatic diamines and heterocyclic monoamines respectively.The structure of the compounds have been confirmed from the spectral data and elemental analysis.The fungicidal and bactericidal activities of the compounds have also been evaluated.