394-60-5

Usage

Uses

Used in Pharmaceutical Industry:
4-(TRIFLUOROMETHYLSULPHINYL)NITROBENZENE is used as a building block for the synthesis of various pharmaceuticals due to its unique chemical structure that can be further modified in chemical reactions to produce a range of medicinal compounds.
Used in Agrochemical Industry:
In the agrochemical sector, 4-(TRIFLUOROMETHYLSULPHINYL)NITROBENZENE is utilized as a key intermediate in the production of pesticides and other agrochemicals, contributing to its effectiveness in controlling pests and diseases in agriculture.

InChI:InChI=1/C7H4F3NO2S/c8-7(9,10)14-6-3-1-5(2-4-6)11(12)13/h1-4H

Upstream product

• 403-66-7 p-nitrophenyl trifluoromethyl sulfide 
• 13088-17-0 4-nitro-benzenesulfinyl chloride 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 456-56-4 phenyl trifluoromethylsulfide 
• 100-32-3 di(p-nitrophenyl) disulfide 

Downstream Products

• 95970-31-3 C₈H₄F₆N₂O₄S₂ 
• 95448-39-8 imino(4-nitrophenyl)(trifluoromethyl)-λ⁶-sulfanone 
• 708-67-8 4-aminophenyl trifluoromethylsulfoxide 
• 426-58-4 (trifluoromethylsulfonyl)benzene 
• 456-56-4 phenyl trifluoromethylsulfide 
• 703-18-4 phenyl trifluoromethyl sulfoxide 
• 1948-06-7 <3-Nitro-phenyl>-trifluormethyl-sulfoxid 
• 942-39-2 1-fluoro-4-((trifluoromethyl)sulfinyl)benzene 
• 1948-05-6 (3-Amino-phenyl)-trifluormethyl-sulfoxid 
• 1092380-24-9 S-(trifluoromethyl)-4-nitrophenylphenylsulfonium triflate 
• 95970-26-6 S-Trifluoromethyl-S-p-(4-dimethylaminophenylazo)phenyl-N-trifluoromethylsulfonylsulfimide 
• 95970-25-5 s-Trifluoromethyl-S-p-aminophenyl-N-trifluoromethylsulfonylsulfimide 

Relevant academic research and scientific papers

Selective oxidation and chlorination of trifluoromethylsulfide using trichloroisocyanuric acid in ionic liquid

A route to chemoselective oxidation and chlorination of aryltrifluoromethylsulfide using trichloroisocyanuric acid (TCCA) in ionic liquid, an efficiently O-methylation reaction and a reduction of nitro- to amido- in excellent yields have been developed.

Convenient one-pot procedure for converting aryl sulfides to nitroaryl sulfones

When treated with nitrogen dioxide and ozone in inert solvent at 0°C or below, aryl sulfides underwent smooth oxidative nitration to give nitroaryl sulfones in good yield. Using this methodology, a series of mono- and di-nitrated aryl sulfones were prepared from methyl phenyl sulfide and diphenyl sulfide and their physical data are presented.

Nucleophilic trifluoromethylation of organic substrates using (trifluoromethyl)trimethylsilane in the presence of a fluoride anion. II. A convenient route to aryltrifluoromethyl-sulfides, - sulfoxides and -sulfones

Aryltrifluoromethyl-sulfides, -sulfoxides and -sulfones can be prepared by trifluoromethylation of the corresponding arylsulfenyl, -sulfinyl and -sulfonyl halides using (trifluoromethyl)trimethylsilane in the presence of fluoride sources, such as TASF . - Keywords: Nucleophilic trifluoromethylation; (Trifluoromethyl)trimethylsilane; Fluoride anion; Aryltrifluoromethylsulfides; Aryltrifluoromethylsulfoxides; Aryltrifluoromethylsulfones