3943-77-9

Basic information

• Product Name: ETHYL 3,4-DIMETHOXYBENZOATE
• Synonyms: 3,4-dimethoxy-benzoicaciethylester;ETHYL 3,4-DIMETHOXYBENZOATE;ethyl veratrate;3,4-Dimethoxybenzoicacidethylester~Ethylveratrate;Ethyl 3,4-dimethoxybenzoate, 98+%;Benzoic acid, 3,4-diMethoxy-, ethyl ester;Veratric acid, ethyl ester;Veratric acid, ethyl ester (7CI,8CI)
• CAS NO: 3943-77-9
• Molecular Formula: C11H14O4
• Molecular Weight: 210.23
• EINECS: 223-526-4
• Mol File: 3943-77-9.mol
• Article Data: 49

Chemical Properties

• Melting Point: 43-44°C
• Boiling Point: 295.5°C (estimate)
• Flash Point: 129.5 °C
• Appearance: /
• Density: 1.1922 (rough estimate)
• Vapor Pressure: 0.00152mmHg at 25°C
• Refractive Index: 1.5020 (estimate)
• BRN: 3118897
• CAS DataBase Reference: ETHYL 3,4-DIMETHOXYBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 3,4-DIMETHOXYBENZOATE(3943-77-9)
• EPA Substance Registry System: ETHYL 3,4-DIMETHOXYBENZOATE(3943-77-9)

Safety Data

• Safety Statements: 22-24/25
• RTECS: DG8690000
• Hazardous Substances Data: 3943-77-9(Hazardous Substances Data)

Usage

General Description

Ethyl 3,4-dimethoxybenzoate is a chemical compound with the molecular formula C12H14O4. It belongs to a specific category of organic compounds known as benzoic acid esters, which are compounds containing a benzene ring where a carbon atom is linked to a carboxyl group (COOH) via an oxygen atom. Its distinct characteristics include a strong floral or tropical fruity scent which makes it useful in the creation of certain fragrances in perfumery. It is also used in the food and beverage industry as a flavoring agent due to its sweet, fruity taste. Ethyl 3,4-dimethoxybenzoate is generally considered stable, non-toxic and not harmful to the environment.

InChI:InChI=1/C11H14O4/c1-4-15-11(12)8-5-6-9(13-2)10(7-8)14-3/h5-7H,4H2,1-3H3

Upstream product

• 91-16-7 1,2-dimethoxybenzene 
• 509-14-8 tetranitromethane 
• 93-15-2 1,2-dimethoxy-4-(2-propenyl)benzene 
• 64-17-5 ethanol 
• 69922-36-7 2-(3,4-dimethoxyphenyl)-1,3-dithiolane 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 21728-28-9 (2-oxo-1,2-dihydro-indol-3-ylidene)-acetic acid ethyl ester 
• 2150-38-1 methyl 3,4-dimethoxybenzoate 
• 10548-77-3 1-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propan-1-one 
• 22675-96-3 2-methoxyphenoxy-3',4'-dimethoxyacetophenone 
• 1835-02-5 2-Bromo-1-(3,4-dimethoxyphenyl)ethanone 
• 140455-40-9 1-(3,4-dimethoxyphenyl)-2-phenoxy-1-ethanone 
• 122775-35-3 3,4-Dimethoxyphenylboronic acid 
• 1609-47-8 diethyl dicarbonate 

Downstream Products

• 74385-18-5 3,4-dimethoxy-(1'-hydroxy-1'-methylethyl)benzene 
• 858834-56-7 1-(3,4-dimethoxy-phenyl)-3-(2,3,4-trimethoxy-phenyl)-propane-1,3-dione 
• 100905-33-7 ethyl 2-nitro-4,5-dimethoxybenzoate 
• 4687-37-0 ethyl 3,4-dimethoxybenzoylacetate 
• 75335-15-8 1-(3,4-dimethoxyphenyl)-3-phenyl-1,3-propanedione 
• 111560-71-5 (+/-)-6exo-methoxy-3exo-veratroyloxy-tropane 
• 111560-71-5 (+/-)-6exo-methoxy-3endo-veratroyloxy-tropane 
• 135940-06-6 2-(3,4-Dimethoxy-phenyl)-8,8-dimethyl-7,8-dihydro-6H-pyrano[3,2-g]chromen-4-one 
• 135940-07-7 8-(3,4-Dimethoxy-phenyl)-5-methoxy-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-f]chromen-10-one 
• 119328-86-8 2-(3,4-Dimethoxy-phenyl)-5-methoxy-8,8-dimethyl-9,10-dihydro-8H-pyrano[2,3-f]chromen-4-one 
• 41764-74-3 3,4-dimethoxybenzohydrazide 
• 13546-91-3 N-hydroxy-3,4-dimethoxybenzamide 
• 52751-63-0 1,3-di-(3,4-dimethoxyphenyl)-1,3-propanedione 
• 167167-93-3 ethyl 2,3-bis(3,4-dimethoxyphenyl)-3-oxopropanoate 

Relevant articles and documents

COMPOUNDS HAVING EXCITED STATE INTRAMOLECULAR PROTON TRANSFER (ESIPT) CHARACTER FOR USE IN TREATING AND/OR PREVENTING SUNBURN AND/OR PREVENTING U.V. DAMAGE

This disclosure relates to use of cashew nut shell liquid (CNSL) phenolics in the manufacture of molecules having ESIPT character, wherein said molecules are UVA and/or UVB absorbers, and further wherein said molecules are formulated as protectants against UVA and/or UVB radiation. The disclosure extends to use of CNSL in the manufacture of compositions including molecules having ESIPT character for treating and/or preventing sunburn and/or preventing U.V. damage.

Regioselective Ring Expansion of 3-Ylideneoxindoles with Tosyldiazomethane (TsDAM): A Metal-Free and Greener Approach for the Synthesis of Pyrazolo-[1,5- c]quinazolines

An efficient, metal-free approach to access pyrazolo-[1,5-c]quinazolines with 3-ylideneoxindoles and tosyldiazomethane (TsDAM) under mild aqueous reaction conditions has been developed and the solvent involvement in the present reaction has also been explored for the first time. This greener approach involves 1,3-dipolar cycloaddition, regioselective ring expansion, followed by the elimination of tosyl group with aqueous base in a single operation, and the product can be isolated in high purity without column chromatographic separation. The method is also compatible with a large variety of functional groups, providing good to excellent yields in water, thus resulting in a decrease of environmental impact in the pharmaceutical industry.

Design, synthesis and molecular docking of new N-4-piperazinyl ciprofloxacin-triazole hybrids with potential antimicrobial activity

New N-4-piperazinyl ciprofloxacin-triazole hybrids 6a-o were prepared and characterized. The in vitro antimycobacterial activity revealed that compound 6a experienced promising antimycobacterial activity against Mycobactrium smegmatis compared with the reference isoniazide (INH). Additionally, compound 6a exhibited broad spectrum antibacterial activity against all the tested strains either Gram-positive or Gram-negative bacteria compared with the reference ciprofloxacin. Also, compounds 6g and 6i displayed considerable antifungal activity compared with the reference ketoconazole. DNA cleavage assay of the highly active compounds 6c and 6h showed a good correlation between the Mycobactrium cleaved DNA gyrase assay and their in vitro antimycobactrial activity. Moreover, molecular modeling studies were done for the designed ciprofloxacin derivatives to predict their binding modes towards Topoisomerase II enzyme (PDB: 5bs8).