39503-57-6

Usage

Uses

Used in Pharmaceutical Industry:
METHYL 5-BROMO-2-HYDROXY-4-METHYLBENZOATE is used as a building block for the synthesis of various drugs and pharmaceutical compounds, contributing to the development of new medications and therapies.
Used in Agrochemical Production:
In the agrochemical industry, METHYL 5-BROMO-2-HYDROXY-4-METHYLBENZOATE is used as an intermediate, playing a crucial role in the production of various agrochemicals that aid in crop protection and enhancement of agricultural yields.
Used in Fine Chemicals Industry:
METHYL 5-BROMO-2-HYDROXY-4-METHYLBENZOATE is also utilized as an intermediate in the synthesis of other fine chemicals, indicating its versatility and importance in the chemical industry for creating specialty products.

Upstream product

• 4670-56-8 methyl 2-hydroxy-4-methylbenzoate 
• 6623-35-4 5-bromo-2-hydroxy-4-methylbenzoic acid 
• 50-85-1 2-hydroxy-p-toluic acid 
• 74-88-4 methyl iodide 
• 77-78-1 dimethyl sulfate 
• 67-56-1 methanol 

Downstream Products

• 1362819-23-5 methyl 2-(acetyloxy)-5-bromo-4-(bromomethyl)benzoate 
• 1362820-01-6 2-((4-fluorobenzyl)oxy)-5-(1-methyl-1H-pyrazol-4-yl)-4-(morpholine-4-carbonyl)benzoic acid 
• 1362821-24-6 2-(benzyloxy)-5-bromo-N-(3-chlorophenyl)-4-(morpholinomethyl)benzamide 
• 1362817-71-7 5-bromo-4-(4-morpholinylmethyl)-2-[(phenylmethyl)oxy]-N-4-pyridazinylbenzamide 
• 1362817-74-0 5-bromo-4-(4-morpholinylmethyl)-2-[(phenylmethyl)oxy]-N-3-pyridinylbenzamide 
• 1362817-76-2 5-(1-methyl-1H-pyrazol-4-yl)-4-(4-morpholinylmethyl)-2-[(phenylmethyl)oxy]-N-4-pyridazinylbenzamide 
• 1362817-77-3 5-(1-methyl-1H-pyrazol-4-yl)-4-(4-morpholinylmethyl)-2-[(phenylmethyl)oxy]-N-3-pyridinylbenzamide 
• 1362817-84-2 4-methyl-5-(1-methyl-1H-pyrazol-4-yl)-2-[(phenylmethyl)oxy]-N-3-pyridinylbenzamide 
• 1362817-86-4 4-methyl-5-(1-methyl-1H-pyrazol-4-yl)-2-[(phenylmethyl)oxy]-N-4-pyridazinylbenzamide 
• 1362818-01-6 5-bromo-2-{[(4-fluorophenyl)methyl]oxy}-4-(4-morpholinylmethyl)-N-3-pyridinylbenzamide 
• 1362818-03-8 5-bromo-2-{[(4-fluorophenyl)methyl]oxy}-N-(3-methyl-4-isoxazolyl)-4-(4-morpholinylmethyl)benzamide 
• 1362818-05-0 2-{[(4-fluorophenyl)methyl]oxy}-5-(1-methyl-1H-pyrazol-4-yl)-4-(4-morpholinylmethyl)-N-3-pyridinylbenzamide 
• 1362818-07-2 2-{[(4-fluorophenyl)methyl]oxy}-N-(3-methyl-4-isoxazolyl)-5-(1-methyl-1H-pyrazol-4-yl)-4-(4-morpholinylmethyl)benzamide 
• 1362818-09-4 5-bromo-2-{[(2,4-difluorophenyl)methyl]oxy}-4-(4-morpholinylmethyl)-N-3-pyridinylbenzamide 

Relevant academic research and scientific papers

Big catkin willow acids compounds and medical use

The invention discloses a AMPK agonist activity with salicylic acid compound and its preparation method and medical use, it is the structural formula of the formula (I) compound of formula, its pharmaceutically acceptable salt or prodrug or solvate. The structure of the invention of formula (I) compound of formula activated AMPK, therefore can be used for preparing the prevention or treatment of AMPK mediated diseases.

POLYCYCLIC AMIDES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS

The present invention relates to compounds of formula (I), or their isotopic forms, stereoisomers, tautomers or pharmaceutically acceptable salt (s) thereof as muscarinic M1 receptor positive allosteric modulators (M1 PAMs). The present invention describes the preparation, pharmaceutical composition and the use of compound formula (I).

APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS AND USES THEREOF

Described herein are ASK1 inhibitors and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for the treatment of blood disease, autoimmune disorders, pulmonary disorders, hypertension, inflammatory diseases, fibrotic diseases, diabetes, diabetic nephropathy, renal diseases, respiratory diseases, cardiovascular diseases, acute lung injuries, acute or chronic liver diseases, and neurodegenerative diseases.

NITROGEN-CONTAINING TRICYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE

A nitrogen-containing tricyclic compound which acts as modulator of FXR, or a stereoisomer, a geometric isomer, a tautomer, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, and the use of the compoun

Rational approach to highly potent and selective apoptosis signal-regulating kinase 1 (ASK1) inhibitors

Many diseases are believed to be driven by pathological levels of reactive oxygen species (ROS) and oxidative stress has long been recognized as a driver for inflammatory disorders. Apoptosis signal-regulating kinase 1 (ASK1) has been reported to be activ

OXABOROLE ESTERS AND USES THEREOF

The present invention provides oxaborole ester compounds and compositions thereof which are useful to treat diseases associated with parasites, such as Chagas Disease and African Animal Trypanosomosis.

2,3-DIHYDRO-4H-1,3-BENZOXAZIN-4-ONE DERIVATIVES AS MODULATORS OF CHOLINERGIC MUSCARINIC M1 RECEPTOR

The present invention provides a compound having a cholinergic muscarinic M1 receptor positive allosteric modulator activity, which may be useful as a prophylactic or therapeutic drug for Alzheimer's disease, schizophrenia, pain, sleep disorder, Parkinson's disease dementia, dementia with Lewy bodies and the like. The present invention relates to a compound represented by the formula (I) or a salt thereof: wherein each symbol is as defined in the attached DESCRIPTION.

ISOINDOLINE-1-ONE DERIVATIVES AS CHOLINERGIC MUSCARINIC M1 RECEPTOR POSITIVE ALLOESTERIC MODULATOR ACTIVITY FOR THE TREATMENT OF ALZHEIMERS DISEASE

The present invention provides a compound having a cholinergic muscarinic M1 receptor positive allosteric modulator activity and useful as an agent for the prophylaxis or treatment of Alzheimer's disease, schizophrenia, pain, sleep disorder, Parkinson's disease dementia, dementia with Lewy bodies, and the like. The present invention relates to a compound represented by the formula (I) or a salt thereof. (I) wherein each symbol is as described in the specification, or a salt thereof.

2 - (BENZYLOXY) BENZAMIDES AS LRRK2 KINASE INHIBITORS

The present invention relates to novel compounds that inhibit LRRK2 kinase activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by LRRK2 kinase activity, for example Parkinson's disease or Alzheimer's disease.

A simple and effective method for chemoselective esterification of phenolic acids

A new method for efficient and chemoselective esterification of phenolic acids in KHCO3/alkyl halide/DMF reaction system is described, by which a series of phenoic acid esters were obtained in excellent yields.