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NSC54180, also known as 1-(3-chlorophenyl)-2-(4-fluorophenyl)-2-hydroxyethanone, is a synthetic organic compound with potential applications in pharmaceutical research. It is a derivative of the class of compounds known as β-ketoenones, which are characterized by the presence of a carbonyl group adjacent to a carbon-carbon double bond. NSC54180 has been studied for its potential biological activities, such as anti-inflammatory and anticancer properties, although its specific mechanisms of action and therapeutic potential are not fully established. The compound is part of the National Cancer Institute's (NCI) database of small molecules, which are screened for various biological activities, and it serves as a starting point for further research and development in the field of drug discovery.

6623-35-4

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6623-35-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6623-35-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,6,2 and 3 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6623-35:
(6*6)+(5*6)+(4*2)+(3*3)+(2*3)+(1*5)=94
94 % 10 = 4
So 6623-35-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H7BrO3/c1-4-2-7(10)5(8(11)12)3-6(4)9/h2-3,10H,1H3,(H,11,12)

6623-35-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-bromo-2-hydroxy-4-methylbenzoic acid

1.2 Other means of identification

Product number -
Other names 5-bromo-2-hydroxy-4-methyl-benzoic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6623-35-4 SDS

6623-35-4Relevant academic research and scientific papers

Big catkin willow acids compounds and medical use

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Paragraph 0077; 0079; 0080, (2019/05/28)

The invention discloses a AMPK agonist activity with salicylic acid compound and its preparation method and medical use, it is the structural formula of the formula (I) compound of formula, its pharmaceutically acceptable salt or prodrug or solvate. The structure of the invention of formula (I) compound of formula activated AMPK, therefore can be used for preparing the prevention or treatment of AMPK mediated diseases.

NITROGEN-CONTAINING TRICYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE

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Page/Page column 80; 81, (2018/03/01)

A nitrogen-containing tricyclic compound which acts as modulator of FXR, or a stereoisomer, a geometric isomer, a tautomer, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, and the use of the compoun

PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF

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Paragraph 0892, (2018/05/24)

The present invention provides compounds, compositions thereof, and methods of using the same.

2,3-DIHYDRO-4H-1,3-BENZOXAZIN-4-ONE DERIVATIVES AS MODULATORS OF CHOLINERGIC MUSCARINIC M1 RECEPTOR

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Paragraph 0393, (2017/01/09)

The present invention provides a compound having a cholinergic muscarinic M1 receptor positive allosteric modulator activity, which may be useful as a prophylactic or therapeutic drug for Alzheimer's disease, schizophrenia, pain, sleep disorder, Parkinson's disease dementia, dementia with Lewy bodies and the like. The present invention relates to a compound represented by the formula (I) or a salt thereof: wherein each symbol is as defined in the attached DESCRIPTION.

ISOINDOLINE-1-ONE DERIVATIVES AS CHOLINERGIC MUSCARINIC M1 RECEPTOR POSITIVE ALLOESTERIC MODULATOR ACTIVITY FOR THE TREATMENT OF ALZHEIMERS DISEASE

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Paragraph 0349, (2015/11/10)

The present invention provides a compound having a cholinergic muscarinic M1 receptor positive allosteric modulator activity and useful as an agent for the prophylaxis or treatment of Alzheimer's disease, schizophrenia, pain, sleep disorder, Parkinson's disease dementia, dementia with Lewy bodies, and the like. The present invention relates to a compound represented by the formula (I) or a salt thereof. (I) wherein each symbol is as described in the specification, or a salt thereof.

2-IMINOPYRROLIDINE DERIVATES

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Page 84, (2008/06/13)

A 2-iminopyrrolidine derivative represented by the formula: {wherein ring B represents a benzene ring, pyridine ring, etc.; R101 - R103 represent hydrogen, halogen, C1-6 alkyl, etc.; R5 represents hydrogen, C1-6 alkyl, C1-6 alkoxy-C1-6 alkyl, etc.; R6 represents hydrogen, C1-6 alkyl, C1-6 alkyloxycarbonyl, etc.; Y1 represents a single bond, -CH2-, etc.; Y2 represents a single bond, -CO-, etc.; and Ar represents hydrogen, a group represented by the formula: [wherein R10-R14 represent hydrogen, C1-6 alkyl, hydroxyl, C1-6 alkoxy, etc.; and R11 and R12 or R12 and R13 may bond together to form a 5- to 8-membered heterocyclic ring], etc.}, or a salt thereof.

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