39629-30-6Relevant articles and documents
One-Pot Silyl Ketene Acetal-Formation Mukaiyama-Mannich Additions to Imines Mediated by Trimethylsilyl Trifluoromethanesulfonate
Wade Downey,Ingersoll, Jared A.,Glist, Hadleigh M.,Dombrowski, Carolyn M.,Barnett, Adam T.
supporting information, p. 7287 - 7291 (2015/11/25)
In the presence of trimethylsilyl trifluoromethanesulfonate and trialkylamine base, thioesters are readily converted into silyl ketene acetals in situ and undergo Mukaiyama-Mannich addition to N-phenylimines in one pot. The silyl triflate appears to play
PREPARATION OF ORGANOZINC HALIDES FROM REACTIVE HALOGEN COMPOUNDS AND THEIR USE
-
, (2008/06/13)
A process for preparing organozinc halides in solvents, includes reacting a reactive halogen compound with zinc in one or more carboxylic esters. It is also possible to prepare keto, hydroxyl and amino compounds of organozinc halides obtained in a first step from a reactive halogen compound and zinc in one or more carboxylic esters, wherein the organozinc halide obtained is reacted in a second step with an electrophilic reaction partner and the reaction product of the second step is hydrolyzed in a third step.
A simple one-pot three-component reaction for preparation of secondary amines and amino esters mediated by lithium perchlorate
Saidi, Mohammad R,Azizi, Najmoddin,Zali-Boinee, Hasan
, p. 6829 - 6832 (2007/10/03)
The one-pot synthesis of several secondary amines and secondary amino esters are reported. Treatment of aldehydes (aliphatic or aromatic) with (trimethylsilyl)alkylamines, in the presence of 5 M lithium perchlorate in diethyl ether gives intermediate imines. Reaction of these intermediate imines with different nucleophiles and functionalized organozinc reagents, BrZnCH2COOR, produce a variety of secondary amines and N-alkyl- or N-arylamino esters in good yields.
