39629-48-6Relevant academic research and scientific papers
Highly diastereoselective addition reaction of ketene silyl acetals to imines catalyzed by samarium(III) iodide
Hayakawa, Ryuuichirou,Shimizu, Makoto
, p. 591 - 592 (1999)
In the presence of a catalytic amount of a samarium(III) iodide, the addition reaction of ketene silyl acetal to imine afforded the corresponding β-aminoester with high antiselectivity. The reaction of chiral imine under the same conditions gave β-aminoes
Iridium-Catalyzed Reductive Alkylations of Secondary Amides
Ou, Wei,Han, Feng,Hu, Xiu-Ning,Chen, Hang,Huang, Pei-Qiang
supporting information, p. 11354 - 11358 (2018/08/28)
Reported herein is the first direct, metal-catalyzed reductive functionalization of secondary amides to give functionalized amines and heterocycles. The method is shown to have exceptionally broad scope with respect to suitable nucleophiles, which cover both hard and soft C nucleophiles as well as a P nucleophile. The reaction exhibits good chemoselectivity and tolerates several sensitive functional groups.
A convenient imino aldol reaction in ethyl alcohol catalyzed by a cation-exchange resin
Shimizu,Itohara,Hase
, p. 2318 - 2319 (2007/10/03)
Imino aldol reaction of ketene silyl acetals with imines proceeds smoothly to give β-amino esters in good yields under the influence of a cation-exchange resin in ethanol, and the work-up of the reaction consists only of a simple filtration followed by co
