39629-53-3

Upstream product

• 6335-76-8 3-amino-3-phenylpropionic acid ethyl ester 
• 100-44-7 benzyl chloride 
• 100-52-7 benzaldehyde 
• 105-36-2 ethyl bromoacetate 
• 100-46-9 benzylamine 
• 1071-46-1 hydrogen ethyl malonate 
• 2182-52-7 benzylamine acetic acid 
• 4192-77-2 ethyl cinnamate 
• 14191-09-4 ethyl (2Z)-3-(benzylamino)-3-phenylacrylate 
• 1485-70-7 N-benzylbenzamide 
• 3646-50-2 3-Amino-3-phenylpropionic acid 
• 103-36-6 ethyl 3-phenyl-2-propenoate 

Downstream Products

• 19340-71-7 1-benzyl-4-phenyl-2-azetidinone 
• 616-45-5 2-pyrrolidinon 
• 675-20-7 piperidin-2-one 
• 80095-91-6 ethyl 3-(methylthio)-3-phenylpropanoate 
• 80105-61-9 N-benzyl 3-methylthio-3-phenylpropionamide 
• 7544-88-9 2-benzyliminopyrrolidine 
• 62740-75-4 N-benzyl-1-phenylpentan-1-amine 

Relevant academic research and scientific papers

Iridium-Catalyzed Reductive Nucleophilic Addition to Secondary Amides

An iridium-catalyzed reductive nucleophilic addition to secondary amides is reported. After the iridium-catalyzed reduction, the resulting imines can undergo the Strecker reaction, the Mannich reaction, allylation, and [3 + 2]-cycloaddition. The method sh

Hydrogenation of β-N-substituted and β-N,N-disubstituted enamino esters in the presence of iridium(I) catalyst

Several new β-amino esters were prepared in two simple steps from β-keto ester derivatives and primary and secondary amines under mild conditions. The hydrogenation of various enamino esters was performed at 50°C in the presence of iridium catalysts. The new β-N-substituted amino esters were isolated in high yields. Georg Thieme Verlag Stuttgart.

Practical, highly enantioselective chemoenzymatic one-pot synthesis of short-chain aliphatic β-amino acid esters

A practical, highly enantioselective method for the synthesis of short-chain aliphatic β-amino acid esters was developed starting from prochiral and easily accessible substrates. This chemoenzymatic approach is based on a nonenzymatic aza-Michael addition

ZrOCl2·8H2O on montmorillonite K10 accelerated conjugate addition of amines to α,β-unsaturated alkenes under solvent-free conditions

At room temperature, ZrOCl2·8H2O on montmorillonite K10 efficiently catalyzes conjugate addition of amines to a variety of conjugated alkenes such as α,β-unsaturated carbonyl compounds, carboxylic esters, nitriles and amides under solvent-free conditions. The catalyst can be recycled for subsequent reactions without any appreciable loss of efficiency.

Solvent-free stereoselective synthesis of β-aryl-β-amino acid esters by the Rodionov reaction using microwave irradiation

A rapid method for the title synthesis of β-aryl-β-amino acid esters was developed, and the absolute configurations of newly formed C-3 chiral centres in the major and minor diastereomers of the resulting ethyl N-[(S)-α-methylbenzyl]-β-amino-β-phenyl-propionate were determined.