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4-piperidine-carboxamide hydrochloride, also known as PHA-543613, is a chemical compound with significant pharmacological effects, particularly in the field of neuroscience. It is a selective alpha-7 nicotinic acetylcholine receptor agonist, which means it binds to and activates specific receptors in the brain that are involved in cognitive function and memory. 4-piperidine-carboxamide hydrochloride has demonstrated potential therapeutic applications in various neurological and psychiatric conditions due to its ability to enhance cholinergic neurotransmission, as well as its potential anti-inflammatory and neuroprotective properties.

39674-99-2

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39674-99-2 Usage

Uses

Used in Pharmaceutical Industry:
4-piperidine-carboxamide hydrochloride is used as a pharmacological agent for its potential therapeutic effects on conditions such as Alzheimer's disease, schizophrenia, and attention deficit hyperactivity disorder (ADHD). Its ability to enhance cholinergic neurotransmission makes it a promising candidate for the treatment of cognitive impairments and memory deficits associated with these disorders.
Used in Neurological Disorder Treatment:
4-piperidine-carboxamide hydrochloride is used as a potential treatment for neurological disorders due to its neuroprotective properties. It has been investigated for its potential to protect neurons from damage and degeneration, which could be beneficial in conditions characterized by neuronal loss, such as Alzheimer's disease.
Used in Psychiatric Disorder Treatment:
4-piperidine-carboxamide hydrochloride is used as a potential treatment for psychiatric disorders, such as schizophrenia, where cognitive deficits are a significant component of the condition. Its ability to modulate neurotransmission may help improve cognitive function and overall symptom management in individuals with psychiatric disorders.
Used in Drug Development Research:
4-piperidine-carboxamide hydrochloride is used as a compound of interest in the development of novel drug treatments for neurological and psychiatric conditions. Its multifaceted properties, including its agonistic effect on alpha-7 nicotinic acetylcholine receptors, anti-inflammatory, and neuroprotective actions, make it a valuable target for research and drug development efforts aimed at improving treatment options for various brain-related disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 39674-99-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,6,7 and 4 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 39674-99:
(7*3)+(6*9)+(5*6)+(4*7)+(3*4)+(2*9)+(1*9)=172
172 % 10 = 2
So 39674-99-2 is a valid CAS Registry Number.

39674-99-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name piperidine-4-carboxamide,hydrochloride

1.2 Other means of identification

Product number -
Other names piperidine-4-carboxamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:39674-99-2 SDS

39674-99-2Relevant academic research and scientific papers

Aromatic heterocyclic derivatives and applications of aromatic heterocyclic derivatives in medicines

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, (2016/10/09)

The present invention discloses aromatic heterocyclic derivatives and applications of the aromatic heterocyclic derivatives in medicines, and specifically provides a class of aromatic heterocyclic compounds or stereoisomers, geometric isomers, tautomers, racemic bodies, nitrogen oxides, hydrates, solvates, metabolites, pharmaceutically acceptable salts or prodrugs thereof, and pharmaceutical compositions containing the compounds. The present invention further discloses uses of the compounds or pharmaceutical compositions in drug preparation, wherein the drug is used for treatment of respiratory diseases, particularly chronic obstructive pulmonary disease (COPD).

HETEROAROMATIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF

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Paragraph 00540, (2016/05/02)

Disclosed are heteroaryl derivatives, pharmaceutical composition and uses in the manufacture of a medicine for treating respiratory diseases, especially for chronic obstructive pulmonary disease (COPD).

A highly efficient Pd-C catalytic hydrogenation of pyridine nucleus under mild conditions

Cheng, Chuanjie,Xu, Jimin,Zhu, Rui,Xing, Lixin,Wang, Xinyan,Hu, Yuefei

supporting information; experimental part, p. 8538 - 8541 (2009/12/24)

A synergistic Pd-C catalytic hydrogenation of 4-pyridinecarboxamides straightforward to 4-piperidinecarboxamide hydrochlorides was developed in the presence of ClCH2CHCl2. It provided a novel strategy for highly efficient hydrogenati

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