39732-01-9

Usage

Uses

Used in Pharmaceutical Industry:
2-Furan-2-yl-benzoic acid methyl ester is used as a starting material for the synthesis of various pharmaceuticals due to its unique chemical structure and properties, contributing to the development of new drugs with potential therapeutic benefits.
Used in Agrochemical Industry:
Similarly, in the agrochemical sector, 2-Furan-2-yl-benzoic acid methyl ester serves as a key starting material for the synthesis of different agrochemicals, potentially enhancing crop protection and yield.
Used in Anti-inflammatory Applications:
2-Furan-2-yl-benzoic acid methyl ester is studied for its potential anti-inflammatory properties, suggesting its use as a therapeutic agent for conditions characterized by inflammation.
Used in Anti-cancer Applications:
2-FURAN-2-YL-BENZOIC ACID METHYL ESTER is also being investigated for its anti-cancer properties, indicating its potential use in oncology for the development of novel cancer treatments.

InChI:InChI=1/C12H10O3/c1-14-12(13)10-6-3-2-5-9(10)11-7-4-8-15-11/h2-8H,1H3

Upstream product

• 67-56-1 methanol 
• 16191-32-5 2-(2-furanyl)-benzaldehyde 
• 95667-98-4 methyl 2-((methylsulfonyl)oxy)benzoate 
• 610-94-6 2-bromobenzoic acid methyl ester 
• 118486-94-5 2-(tributylstannyl)furan 
• 13331-23-2 fur-2-ylboronic acid 
• 119-36-8 methyl salicylate 
• 134-20-3 2-carbomethoxyaniline 
• 110-00-9 furan 
• 342-54-1 2-(methoxycarbonyl)benzenediazonium tetrafluoroborate 
• 331942-47-3 2-(furan-2-yl)benzoic acid 

Downstream Products

• 331942-47-3 2-(furan-2-yl)benzoic acid 
• 299442-23-2 o-(5-formyl-2-furyl)benzonitrile 
• 1215172-73-8 2-(furan-2-yl)benzoyl chloride 
• 155395-45-2 2-(furan-2-yl)benzonitrile 
• 897446-32-1 N-(2-aminophenyl)-2-furan-2-ylbenzamide 

Relevant academic research and scientific papers

Identification of ortho-Substituted Benzoic Acid/Ester Derivatives via the Gas-Phase Neighboring Group Participation Effect in (+)-ESI High Resolution Mass Spectrometry

Benzoic acid/ester/amide derivatives are common moieties in pharmaceutical compounds and present a challenge in positional isomer identification by traditional tandem mass spectrometric analysis. A method is presented for exploiting the gas-phase neighbor

Compound containing five-member-cycle structure and organic electroluminescence device thereof

The invention provides an organic electroluminescence compound containing a five-number-cycle structure. The compound is high in heat stability, high in luminous efficiency, and high in lighting purity, can be used for manufacturing an organic electrolumi

Synthesis and biological evaluation of benzimidazole derivatives as potent AMP-activated protein kinase activators

Design, synthesis and structure-activity relationships of benzimidazole derivatives as activators of the AMP-activated protein kinase (AMPK) are presented in this paper. AMPK is the central component of a protein kinase cascade that plays a key role in the regulation of energy balance. Once activated, AMPK initiates a series of responses that are aimed at restoring the energy balance of the cell and recent studies have indicated that AMPK plays an important role in regulation of the whole-body energy metabolism. The following study based on the lead compound S27847 involved modification of three regions of this compound. Preliminary structure-activity relationships are being described.

Scope and limitation of the nickel-catalyzed coupling reaction between lithium borates and mesylates

Coupling reaction of aryl borates and mesylates derived from phenols and enols was studied. Mesylates with an electron-with-drawing group or ring were highly reactive at room temperature in the presence of NiCl2(PPh3)2 to furnish the coupling products in good yields.

Stille couplings in supercritical CO2 catalyzed with perfluoro-tagged and un-tagged Pd complexes

Stille CC-couplings in supercritical CO2 (scCO2) were performed with perfluoro-tagged and un-tagged Pd complexes in high yields. With fluoro-tagged complexes yields were generally slightly higher. A recycling of the perfluoro-tagged catalyst was also achieved.

Exploiting poly(ethylene glycol) as a matrix for liquid-phase organic synthesis

Soluble polymer-supported chemistry is a technology that allows the blending of the benefits of polymer-supported synthesis and solution-phase chemistry. Herein, we describe our recent efforts in this area targeted at exploring the scope of poly(ethylene glycol) (PEG) as the matrix. Specifically we describe the use of PEG as a support for triphenyl phosphine and for the Stille reaction.

Nickel-catalyzed coupling reaction of lithium organoborates and aryl mesylates possessing an electron withdrawing group

In the presence of NiCl2(PPh3)2 as catalyst, p-methoxycarbonylphenyl mesylate (5) and tosylate (6) react with lithium arylborates 4 (Ar = 2-furyl, Ph, p-Me-Ph, p-MeO-Ph) at room temperature to afford the coupling products in high yields. Similarly, mesylates 9-11 coupled with these borates 4 efficiently.