39736-28-2

Basic information

• Product Name: 4-AMINO-2-METHYLTHIOTHIAZOLE-5-CARBONITRILE
• Synonyms: 4-AMINO-2-(METHYLSULFANYL)-1,3-THIAZOLE-5-CARBONITRILE;4-AMINO-2-METHYLTHIOTHIAZOLE-5-CARBONITRILE;4-amino-2-(methylthio)-5-Thiazolecarbonitrile
• CAS NO: 39736-28-2
• Molecular Formula: C5H5N3S2
• Molecular Weight: 171.24
• Mol File: 39736-28-2.mol
• Article Data: 8

Chemical Properties

• Melting Point: 202-204°C
• Boiling Point: 401.3±55.0 °C(Predicted)
• Appearance: /
• Density: 1.46±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: -0.20±0.10(Predicted)
• CAS DataBase Reference: 4-AMINO-2-METHYLTHIOTHIAZOLE-5-CARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-2-METHYLTHIOTHIAZOLE-5-CARBONITRILE(39736-28-2)
• EPA Substance Registry System: 4-AMINO-2-METHYLTHIOTHIAZOLE-5-CARBONITRILE(39736-28-2)

Safety Data

• Hazardous Substances Data: 39736-28-2(Hazardous Substances Data)

Usage

General Description

4-Amino-2-methylthiothiazole-5-carbonitrile is a chemical compound with the molecular formula C4H5N3S2. It is a yellow powder that is used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 4-AMINO-2-METHYLTHIOTHIAZOLE-5-CARBONITRILE has potential applications in the field of medicinal chemistry due to its ability to act as a building block for the synthesis of various drug molecules. It is also known for its use in the synthesis of organic molecules, particularly those with biological activity. Additionally, 4-Amino-2-methylthiothiazole-5-carbonitrile has been studied for its antimicrobial and anti-tumor properties, making it a compound of interest in the development of new therapeutic agents.

Upstream product

• 10191-61-4 potassium S-methyl N-cyanocarbamodithioate 
• 107-14-2 chloroacetonitrile 
• 82060-31-9 C₃H₆N₄O₂S₂ 
• 10191-60-3 dimethyl N-cyanodithioiminocarbonate 
• 10191-68-1 C₅H₅N₃S₂ 

Downstream Products

• 120891-11-4 4-chloro-2-(methylsulfanyl)-1,3-thiazole-5-carbonitrile 
• 1361961-48-9 5-(difluoro-(4-fluorophenyl)methyl)-N-(5-methyl-1H-pyrazol-3-yl)-2-(methylsulfinyl)thiazolo[4,5-d]pyrimidin-7-amine 
• 1361961-46-7 5-(difluoro-(4-fluorophenyl)methyl)-2-(methylthio)thiazolo[4,5-d]pyrimidin-7(6H)-one 
• 1361961-47-8 7-chloro-5-(difluoro-(4-fluorophenyl)methyl)-2-(methylthio)thiazolo[4,5-d]pyrimidine 
• 1361960-75-9 5-(difluoro-(4-fluorophenyl)methyl)-N-(5-methyl-1H-pyrazol-3-yl)-2-(methylthio)thiazolo[4,5-d]pyrimidin-7-amine 
• 39736-30-6 4-amino-2-(methylsulfanyl)-1,3-thiazole-5-carboxamide 
• 119011-56-2 7-Chlor-2-(methylthio)thiazolo<4,5-d>pyrimidin 

Relevant articles and documents

NOVEL BICYCLIC HETEROCYCLIC COMPOUND

Provided are a novel compound having a superior inhibitory action on KAT-II, a production method thereof, use thereof, and a pharmaceutical composition containing the aforementioned compound and the like. A compound represented by the formula (I) or a pharmacologically acceptable salt thereof. wherein each symbol is as defined in the DESCRIPTION.

Synthesis and evaluation of 2,7-diamino-thiazolo[4,5-d] pyrimidine analogues as anti-tumor epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors

2,7-Diamino-thiazolo[4,5-d]pyrimidine analogues were synthesized as novel epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors. Representative compounds showed potent and selective EGFR inhibitory activities and inhibited in vitro cellular p

THIAZOLOPYRIMIDINE KINASE INHIBITORS

The present invention is directed to novel thiazolopyrimidine compounds of Formula (I) or a form or composition thereof, and the use thereof as inhibitors of ATP-protein kinase interactions.