39748-15-7Relevant articles and documents
Chiral trans-carboxylic trifluoromethyl 2-imidazolines by a Ag2O-catalyzed Mannich-type reaction
Trulli, Laura,Sciubba, Fabio,Fioravanti, Stefania
, p. 572 - 577 (2018)
Trifluoromethyl aldimines derived from α-amino esters have proven to be very good starting materials to obtain the title compounds. A Ag2O-catalyzed Mannich-type/cyclization cascade reaction starting from suitable α-isocyano acetates leads to e
Investigation of the configurational stabilities of chiral isocyanoacetates in multicomponent reactions
Carney, Daniel W.,Truong, Jonathan V.,Sello, Jason K.
, p. 10279 - 10285 (2012/02/14)
Isocyanoacetates are uniquely reactive compounds characterized by an ambivalent isocyano functional group and an enolizable α-carbon. It is widely believed that chiral α-substituted isocyanoacetates are configurationally unstable in some synthetically use