3982-72-7

Basic information

• Product Name: Cbz-Gly-L-Phe-L-Leu-OEt
• Synonyms: Cbz-Gly-L-Phe-L-Leu-OEt
• CAS NO: 3982-72-7
• Molecular Weight: 497.591
• Mol File: 3982-72-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Cbz-Gly-L-Phe-L-Leu-OEt(CAS DataBase Reference)
• NIST Chemistry Reference: Cbz-Gly-L-Phe-L-Leu-OEt(3982-72-7)
• EPA Substance Registry System: Cbz-Gly-L-Phe-L-Leu-OEt(3982-72-7)

Safety Data

• Hazardous Substances Data: 3982-72-7(Hazardous Substances Data)

Upstream product

• 2953-42-6 Z-phenylalanylleucine ethyl ester 
• 1138-80-3 N-(Benzyloxycarbonyl)glycine 
• 1161-13-3 N-Cbz-L-Phe 
• 2743-40-0 L-leucine ethyl ester hydrochloride 
• 58889-73-9 (S)-N-benzyloxycarbonyl-leucine ethyl ester 

Relevant articles and documents

Tandem deprotection/coupling for peptide synthesis in water at room temperature

A tandem deprotection/coupling sequence is reported for solution-phase peptide synthesis in water under micellar catalysis conditions using the designer surfactant TPGS-750-M. Cbz deprotection followed by peptide coupling in the presence of COMU and 2,6-lutidine afforded polypeptides containing up to 10 amino acid residues. A broad scope characterizes this new technology. No epimerization has been detected. The associated E Factors, as a measure of "greenness" and known to be extremely high for peptide couplings, have been reduced to less than 10 due to the step-economy and minimal amounts of organic solvent needed for product extraction.