39828-47-2 Usage
Uses
Used in Pharmaceutical Industry:
2-OXO-2,3-DIHYDRO-1H-IMIDAZOLE-4-CARBOXYLIC ACID is used as a reactant in the enantioselective strategy to the spirocyclic core of palau'amine and related bisguanidine marine alkaloids. These alkaloids are of significant interest in the pharmaceutical industry due to their potent biological activities, including anti-cancer properties. The enantioselective synthesis of these compounds allows for the development of more effective and selective drugs with fewer side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 39828-47-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,8,2 and 8 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 39828-47:
(7*3)+(6*9)+(5*8)+(4*2)+(3*8)+(2*4)+(1*7)=162
162 % 10 = 2
So 39828-47-2 is a valid CAS Registry Number.
InChI:InChI=1/C4H4N2O3/c7-3(8)2-1-5-4(9)6-2/h1H,(H,7,8)(H2,5,6,9)
39828-47-2Relevant academic research and scientific papers
Synthesis and Biological Activity of 9-Mercaptodethiobiotin - a Putative Biotin Precursor in Escherichia coli
Baxter, Robert L.,Camp, Dominic J.,Coutts, Andrew,Shaw, Nicholas
, p. 255 - 258 (2007/10/02)
A total synthesis of (+/-)-9-mercaptodethiobiotin 3 via the aldehyde 9 is described.Compound (+/-)-3 does not function as a biotin replacement factor for an E. coli mutant (SA291) lacking the entire biotin synthesis operon (bioABFCD-) but supports growth of an E. coli bioA mutant.Compound (+/-)-3 also supports growth of transformed cells of SA291 carrying a plasmid encoding the E. coli biotin synthase (bioB) gene indicating that the compound may be able to substitute for dethiobiotin 2 as a substrate for biotin synthase.
