39868-14-9Relevant academic research and scientific papers
Evaluation of endo- and exo-aryl-substitutions and central scaffold modifications on diphenyl substituted alkanes as 5-lipoxygenase activating protein inhibitors
Chu, Lin,Armstrong, Helen M.,Chang, Linda L.,Cheng, Amy F.,Colwell, Lawrence,Cui, Jisong,Evans, Jilly,Galka, Amy,Goulet, Mark T.,Hayes, Nancy,Lo, Jane,Menke, John,Ok, Hyun O.,Ondeyka, Debra L.,Patel, Minal,Quaker, Grace M.,Sings, Heather,Witkin, Stephanie L.,Zhao, Annie,Ujjainwalla, Feroze
scheme or table, p. 4133 - 4138 (2012/07/03)
A search for a suitable replacement for the central norbornyl scaffold presented in the recently disclosed novel FLAP inhibitors is herein described, as well as the SAR study performed on the endo and exo-aryl groups.
Friedel-Crafts acylation using bismuth triflate in [BMI][PF6]
Tran, Phuong Hoang,Duus, Fritz,Le, Thach Ngoc
experimental part, p. 222 - 224 (2012/01/30)
Bismuth trifluoromethanesulfonate was found to be a good catalyst for the Friedel-Crafts acylation. Bismuth triflate immobilized in an ionic liquid was the most efficient catalytic system. Bismuth triflate in [BMI][PF6] catalyzes this reaction under microwave irradiation allowing the rapid synthesis of aryl ketones in excellent yields. The catalyst system was easily recovered and reused several times.
Benzoquinones and Related Compounds. Part 2. Preferred Conformations of Some Acyl-1,4-benzoquinones in Solution
Bruce, Malcolm,Heatley, Frank,Ryles, Roderick G.,Scrivens, James H.
, p. 860 - 866 (2007/10/02)
Studies based on polarographic reduction potentials, electronic absorption spectra, and (1)H and (13)C nuclear magnetic relaxation data show that in solution the preferred conformation of formyl-1,4-benzoquinone is that with the formyl and quinonoid groups coplanar, and the formyl carbonyl group anti to the 1-carbonyl, whereas that of acetyl- and pivaloyl-1,4-benzoquinone has the acyl groups approximately perpendicular to the quinonoid ring.
