40036-62-2

Basic information

• Product Name: (3-methylpent-1-ynyl)benzene
• CAS NO: 40036-62-2
• Molecular Weight: 158.243
• Mol File: 40036-62-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (3-methylpent-1-ynyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (3-methylpent-1-ynyl)benzene(40036-62-2)
• EPA Substance Registry System: (3-methylpent-1-ynyl)benzene(40036-62-2)

Safety Data

• Hazardous Substances Data: 40036-62-2(Hazardous Substances Data)

Upstream product

• 1113-78-6 tri(sec-butyl)borane 
• 536-74-3 phenylacetylene 
• 598-30-1 sec.-butyllithium 
• 28995-88-2 1-methyl-4-((phenylethynyl)sulfonyl)benzene 
• 15366-08-2 s-butylmagnesium chloride 
• 1966-65-0 3-methyl-1-phenyl-1-pentyn-3-ol 

Downstream Products

• 111679-80-2 1-(4-methylhexa-2,3-dien-2-yl)benzene 

Relevant articles and documents

Enabling the Use of Alkyl Thianthrenium Salts in Cross-Coupling Reactions by Copper Catalysis

Alkyl groups are one of the most widely used groups in organic synthesis. Here, a a series of thianthrenium salts have been synthesized that act as reliable alkylation reagents and readily engage in copper-catalyzed Sonogashira reactions to build C(sp3)?C(sp) bonds under mild photochemical conditions. Diverse alkyl thianthrenium salts, including methyl and disubstituted thianthrenium salts, are employed with great functional breadth, since sensitive Cl, Br, and I atoms, which are poorly tolerated in conventional approaches, are compatible. The generality of the developed alkyl reagents has also been demonstrated in copper-catalyzed Kumada reactions.

Arylsulfonylacetylenes as alkynylating reagents

The unexpected anti-Michael addition of RLi to β-substituted sulfonylacetylenes, followed by in situ elimination of the ion sulfinate, allows the alkynylation of C(sp2) and C(sp3). Aryl and heteroaryl acetylenes, enynes, and mono and dialkyl alkynes can be obtained in very high yields under very mild conditions, avoiding the use of transition metals as catalysts and, in many cases, haloderivatives as starting materials. Furthermore, the use of lithium 2-p-tolylsulfinyl benzylcarbanions as nucleophiles of these reactions allows their stereocontrolled alkynylation, affording enantiomerically pure alkynes or enantioenriched allenes depending on the protonating agent (NH4Cl or H2O).

Highly chemoselective calcium-catalyzed propargylic deoxygenation

A calcium-catalyzed direct reduction of propargylic alcohols and ethers has been accomplished by using triethylsilane as a nucleophilic hydride source. At room temperature a variety of secondary propargylic alcohols was deoxygenated to the corresponding h