4004-20-0

Upstream product

• 91568-02-4 ethyl 3-amino-4-cyano-5-((ethoxycarbonyl)methylthio)thiophene-2-carboxylate 
• 75-15-0 carbon disulfide 
• 105-39-5 chloroacetic acid ethyl ester 
• 109-77-3 malononitrile 
• 105-36-2 ethyl bromoacetate 

Downstream Products

• 1031798-26-1 diethyl 3-amino-4-[(triphenylphosphoranylidene)amino]thieno[2,3-b]thiophene-2,5-dicarboxylate 
• 345910-76-1 3,4-dibenzoylaminothieno(2,3-b)thiophene-2,5-dicarboxamide 
• 330855-84-0 bis[4-oxo-3-phenyl-1(H)-2-thioxothieno(3,2-d)pyrimidine] 
• 594875-50-0 C₃₄H₂₆N₁₀O₆S₄ 
• 594875-49-7 C₃₀H₁₆N₁₂O₂S₄ 

Relevant academic research and scientific papers

Phenyl Groups Result in the Highest Benzene Storage and Most Efficient Desulfurization in a Series of Isostructural Metal-Organic Frameworks

A series of isoreticular metal-organic frameworks (MOFs; NENU-511-NENU-514), which all have high surface areas and strong adsorption capacities, have been successfully constructed by using mixed ligands. NENU-513 has the highest benzene capacity of 1687 m

New iminophosphorane-mediated synthesis of thieno[3′,2′:4,5]thieno[3,2-d]pyrimidin-4(3H)-ones and 5H-2,3-dithia-5,7-diaza-cyclopenta[c,d]indenes

Mono(iminophosphorane) 4 was selectively prepared from the reaction of 3,4-diaminothieno[2,3-b]thiophene 3 with excess triphenylphosphine, C2Cl6, and Et3N due to intramolecular double hydrogen bond formation. Mono(iminopho

Efficient one pot preparation of variously substituted thieno[2,3-b]thiophene

An efficient one pot access to variously substituted thieno[2,3-b]thiophene is described. The title compounds were obtained from 1,3-dicarbonyl or equivalent compounds, carbon disulfide and halomethyl derivatives in good to high yields and fully characterized.

SYNTHESIS OF POLYFUSED HETEROCYCLIC SYSTEMS DERIVED FROM FUNCTIONALLY SUBSTITUTED THIENOTHIOPHENE MOIETY

Diethyl 3,4-diaminothienothiophene-2,5-dicarboxylate 1 was converted into the sodium salt of the corresponding acid 2.Compound 2 upon treatment with acetic anhydride furnished the bisoxazinone derivative 3.The reaction of compound 3 with ammonium acetate, hydrazine hydrate or aniline afforded the bispyrimidine derivatives 4, 5, or 6, respectively.The reaction of compound 4 with phosphoryl chloride gave the corresponding chloro derivative 7 which was converted into the corresponding hydrazino derivative 8.Treatment of compound 8 with acetylacetone or ethyl acetoacetate gave compounds 9 or 10, respectively.On the other hand, the reaction of compound 1 with hydrazine hydrate gave the corresponding hydrazide derivative 11 which was also treated with acetylacetone, ethyl acetoacetate, formic acid or acetic anhydride to afford the described compounds 12, 13, 14, or 15, respectively. Key words: Thienothiophene, bisthienoxazine; bisthienopyrimidine, bisthienopyrimidinone; pyrazine; pyrazinone.

SYNTHESIS OF THIENO(2,3-b)THIOPHENES AND RELATED STRUCTURES

Some new functionally substituted thieno(2,3-b)thiophenes and related compounds were obtained in a one-pot reaction using phase transfer catalysis conditions starting with some active nitriles or active methylene compounds, carbon disulphide or phenyl isothiocyanate and α-chlorocarbethoxy, or α-nitrile electrophiles.The structure of the obtained new compounds was assigned.Key words: Thiophene; thienothiophene; dithiolane; thiazolidinone; thiazoline; thienopyrazole; furopyrazole.