40122-37-0

Basic information

• Product Name: 1-p-Tolylcyclopropanol
• Synonyms: 1-p-Tolylcyclopropanol
• CAS NO: 40122-37-0
• Molecular Formula: C₁₀H₁₂O
• Molecular Weight: 148.20168
• Mol File: 40122-37-0.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-p-Tolylcyclopropanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-p-Tolylcyclopropanol(40122-37-0)
• EPA Substance Registry System: 1-p-Tolylcyclopropanol(40122-37-0)

Safety Data

• Hazardous Substances Data: 40122-37-0(Hazardous Substances Data)

Usage

Physical form

White crystalline solid

Odor

Faint

Common uses

Synthetic intermediate in pharmaceuticals and agrochemicals

Chemical structure

Cyclopropane derivative with a tolyl group (benzene ring with a methyl group attached)

Properties

Insecticidal and fungicidal

Applications

Pesticides, fine chemicals, organic synthesis reactions

Safety precautions

May be harmful if ingested, inhaled, or in contact with skin

Upstream product

• 925-90-6 ethylmagnesium bromide 
• 186581-53-3 diazomethane 
• 54731-27-0 1-p-methylphenyl-1-trimethylsiloxyethene 
• 99-75-2 4-methyl-benzoic acid methyl ester 
• 122-00-9 para-methylacetophenone 
• 2386-64-3 ethylmagnesium chloride 
• 539-74-2 Ethyl 3-bromopropionate 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 534-07-6 1,3-Dichloroacetone 
• 60068-20-4 Trimethyl-(1-p-tolyl-cyclopropoxy)-silane 

Downstream Products

• 60068-20-4 Trimethyl-(1-p-tolyl-cyclopropoxy)-silane 
• 1343380-75-5 1-(4'-methylphenyl)-4,4,4-trifluoro-1-butanone 
• 106696-59-7 1-phenyl-6-(p-tolyl)hexane-1,6-dione 
• 5337-93-9 4'-methylpropiophenone 
• 30764-40-0 1-((2,2,6,6-tetramethylpiperidin-1-yl)oxy)propan-2-one 

Relevant articles and documents

Rhodium(III)-Catalyzed Oxidative Cyclization of Oxazolines with Cyclopropanols: Synthesis of Isoindolinones

The synthesis of C3-substituted isoindolin-1-ones from oxazolines and cyclopropanols has been achieved with oxazoline as a bifunctional nucleophilic directing group. The reaction proceeds by the cleavage of three chemical bonds and allows the formation of three new chemical bonds, a C-N bond, a C-C bond, and a C-O bond, in a single step.

Copper-mediated tandem ring-opening/cyclization reactions of cyclopropanols with aryldiazonium salts: Synthesis of: N -arylpyrazoles

A general method for the synthesis of structurally diverse N-arylpyrazoles from readily available cyclopropanols and aryldiazonium salts is disclosed. The reaction was conducted at room temperature within minutes with a broad substrate scope and excellent regioselectivity.

Ni-Catalyzed Denitrogenative Cross-Coupling of Benzotriazinones and Cyclopropanols: An Easy Access to Functionalized β-Aryl Ketones

A novel Ni-catalyzed denitrogenative cross-coupling between benzotriazinones and cyclopropanols is reported herein. This neoteric reactivity allows for the convenient synthesis of β-(o-amido)aryl ketones from readily available starting materials with good yields (up to 93percent) and general substrate scope.