40141-05-7Relevant academic research and scientific papers
Rearrangements of Cycloalkenyl Aryl Ethers
T?rincsi, Mercedesz,Nagy, Melinda,Bihari, Tamás,Stirling, András,Kolonits, Pál,Novak, Lajos
, (2016/05/24)
Rearrangement reactions of cycloalkenyl phenol and naphthyl ethers and the acid-catalyzed cyclization of the resulting product were investigated. Claisen rearrangement afforded 2-substituted phenol and naphthol derivatives. Combined Claisen and Cope rearrangement resulted in the formation of 4-substituted phenol and naphthol derivatives. In the case of cycloocthylphenyl ether the consecutive Claisen and Cope rearrangements were followed by an alkyl migration. The mechanism of this novel rearrangement reaction is also discussed.
Calcium-catalyzed friedel-crafts alkylation at room temperature
Niggemann, Meike,Meel, Matthias J.
supporting information; experimental part, p. 3684 - 3687 (2010/08/04)
Chemical Equatation Representation A novel calcium catalyst was found to efficiently functionalize electron-rich arenes with secondary and tertiary benzylic, propargylic, and allylic alcohols under very mild reaction conditions. The new catalyst system significantly enlarges the scope of the reaction, which was previously limited except for the few examples with secondary benzylic alcohols.
Tailoring aqueous solvents for organic reactions: Heck coupling reactions in high temperature water
Gron,Tinsley
, p. 227 - 230 (2007/10/03)
High temperature water is demonstrated to be an effective solvent for Heck coupling reactions of aromatic halides with cyclic alkenes without the addition of co-solvents or specialized ligands. Reactions in the presence of LiCl and quaternary ammonium salts indicate that the reaction takes place in the aqueous phase.
Hydroalkylation of Phenol to Cyclohexylphenyl in the Presence of Pd-Al2O3 and NaCl-AlCl3 under Hydrogen Pressure
Kamiyama, Tsutomu,Enomoto, Saburo,Inoue, Masami
, p. 450 - 454 (2007/10/02)
The hydroalkylation of phenol (1) in the presence of palladium catalyst and fused salt (NaCl-AlCl3) under hydrogen pressure was carried out.By using 1percent Pd-Al2O3 (1g) and the fused salt (1:1 mol ratio, 6g), 4-cyclohexyphenol (6) was obtained selectively from 1 (30g) in a yield of 31.9 percent at 120 deg C for 4.5 h.Cyclohexylphenols were formed by way of 2-cyclohexen-1-ol and 1.Keywords-hydroalkylation; palladium catalyst; fused salt; phenol; 2-cyclohexylphenol; 4-cyclohexylphenol; 2-cyclohexylcyclohexanone
REACTION OF PHENOL WITH 1,3-CYCLOHEXADIENE IN THE PRESENCE OF ALUMINUM PHENOLATE
Kozlikovskii, Ya. B.,Koshchii, V. A.,Nesterenko, S. A.
, p. 702 - 705 (2007/10/02)
The controlled synthesis of 2- and 2,6-di(2-cyclohexenyl)phenols was realized by the cycloalkenylation of phenol with 1,3-cyclohexadiene in the presence of aluminum phenolate.Alkenylation is accompanied by intramolecular cyclization of the cyclohexenylphe
