40141-14-8Relevant academic research and scientific papers
Method for synthesizing P-isobutoxybenzylamine
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, (2020/08/27)
The invention provides a method for synthesizing p-isobutoxy benzylamine. P-hydroxybenzyl alcohol is used as a raw material; the method comprises the following steps: reacting p-hydroxybenzyl alcoholwith halogenated isobutane to obtain p-isobutoxy benzyl alcohol; according to the method, p-isobutoxybenzylamine is obtained by taking p-isobutoxybenzylamine as a raw material and performing a seriesof steps such as chlorination and ammonolysis, so the use of relatively harsh reduction conditions with certain risk is avoided, and the produced p-isobutoxybenzylamine is high in purity and excellentin quality and is an excellent route with industrial prospect.
Synthesis method for pimavanserin intermediate
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Paragraph 0016; 0032; 0033, (2017/09/01)
The invention discloses a synthesis method for a pimavanserin intermediate. The synthesis method comprises the steps of firstly allowing 4-hydroxybenzaldehyde to react with iso-butyl bromide to obtain 4-isobutoxybenzaldehyde as an initial raw material; an
