401516-10-7

Basic information

• Product Name: Cyclohexanecarboxylic acid, 2-pyridinylmethyl ester
• CAS NO: 401516-10-7
• Molecular Formula: C13H17NO2
• Molecular Weight: 219.283
• Mol File: 401516-10-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Cyclohexanecarboxylic acid, 2-pyridinylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanecarboxylic acid, 2-pyridinylmethyl ester(401516-10-7)
• EPA Substance Registry System: Cyclohexanecarboxylic acid, 2-pyridinylmethyl ester(401516-10-7)

Safety Data

• Hazardous Substances Data: 401516-10-7(Hazardous Substances Data)

Upstream product

• 586-98-1 2-Hydroxymethylpyridine 
• 201230-82-2 carbon monoxide 
• 110-83-8 cyclohexene 
• 141-53-7 sodium formate 
• 401515-97-7 2-pyridylmethyl formate 

Downstream Products

• 712-50-5 Cyclohexyl phenyl ketone 
• 586-98-1 2-Hydroxymethylpyridine 
• 401515-97-7 2-pyridylmethyl formate 
• 346608-06-8 α-methylbenzeneacetic acid 2-pyridinylmethyl ester 
• 346608-05-7 3-phenylpropionic acid 2-pyridinylmethyl ester 

Relevant articles and documents

Halide ions as a highly efficient promoter in the Ru-catalyzed hydroesterification of alkenes and alkynes

(Chemical Equation Presented) The presence of catalytic amounts of halide salts was found to enhance dramatically the reaction efficiency in the Ru-catalyzed hydroesterification of alkenes and alkynes using a chelating 2-pyridylmethyl formate by lowering

Hydroesterification of alkenes with sodium formate and alcohols promoted by cooperative catalysis of Ru3(CO)12 and 2-pyridinemethanol

(Figure Presented) A chelation-assisted hydroesterification reaction of alkenes with sodium formate and alcohols that involves cooperative catalysis by Ru3(CO)12 and 2-pyridinemethanol is described. In this three-component coupling reaction, sodium formate serves as the carbon monoxide source.

A novel chelation-assisted hydroesterification of alkenes via ruthenium catalysis

An efficient and catalytic protocol of hydroesterification of alkenes has been developed without a need for CO atmosphere. With the introduction of the 2-pyridyl moiety as a chelating group in formate, Ru3(CO)12-catalyzed activation of the formyl C-H bond of formate and subsequent addition of the intermediate to alkenes proceeded with almost complete suppression of decarbonylation. Stereoselectivity of the produced one-carbon elongated esters was good to excellent for the formation of the linear adduct depending on the bulkiness of the alkenes used. This procedure could be readily applied to a variety of olefins such as terminal, internal, cyclic, bicyclic, vinyl ether, and conjugated enone systems with high efficiency and selectivity. It was also amenable to a solvent-free condition. On the basis of the chelation-driven C-H bond activation of formate, a putative mechanism of the Ru-catalyzed hydroesterification of 2-pyridylmethyl formate has been proposed. Copyright