40174-37-6

Usage

InChI:InChI=1/C14H11N/c1-10-8-9-15-14-12(10)7-6-11-4-2-3-5-13(11)14/h2-9H,1H3

Upstream product

• 134-32-7 1-amino-naphthalene 
• 67-56-1 methanol 
• 7664-93-9 sulfuric acid 
• 40174-33-2 but-2-ynyl-[1]naphthyl-amine 
• 98-95-3 nitrobenzene 
• 590-90-9 1-Hydroxy-3-butanone 
• 40174-34-3 (3-chloro-but-2ξ-enyl)-[1]naphthyl-amine 
• 1210-07-7 4-methyl-benzo[h]quinolin-2-ol 
• 78-94-4 methyl vinyl ketone 
• 61773-06-6 2-chlor-4-methylbenzo-quinoline 

Downstream Products

• 7498-19-3 C₂₃H₂₀N₂ 
• 6707-23-9 benzo[h]quinoline-4-carboxylic acid 
• 7498-19-3 4-(trans-2-benzo[h]quinolin-4-yl-vinyl)-N,N-dimethyl-aniline 
• 31493-12-6 4-styryl-benzo[h]quinoline 

Relevant academic research and scientific papers

Iodine-catalyzed coupling of β-hydroxyketones with aromatic amines to form β-aminoketones and Benzo[h]quinolones

An iodine-catalyzed coupling of β-hydroxyketones with aromatic amines to yield β-aminoketones and benzo[h]quinolones had been developed. Noble metallic catalysts, oxidants, α β-unsaturated ketone intermediates and aza-Michael addition were not involved in this coupling reaction which made it unique when compared to other reactions reported in literature. Inexpensive iodine catalyst, easy accessible raw materials, mild reaction conditions, good functional group tolerance and excellent selectivity made this coupling reaction be a practical method. This reaction can also be scaled up.

Palladium-catalyzed aerobic oxidative coupling of allylic alcohols with anilines in the synthesis of nitrogen heterocycles

We report herein an unprecedented and expedient Pd-catalyzed oxidative coupling of allyl alcohols with anilines to afford β-amino ketones which are converted into substituted quinolines in a one-pot fashion. The exclusive preference for N-alkylation over N-allylation makes this approach unique when compared to those reported in literature. Detailed mechanistic investigations reveal that the conjugate addition pathway was the predominant one over the allylic amination pathway. The notable aspects of the present approach are the use of readily available, bench-stable allyl alcohols and molecular oxygen as the terminal oxidant, in the process dispensing the need for unstable and costly enones. Further, we explored the synthetic utility of β-amino ketones through an intramolecular α-arylation methodology and a one-pot domino annulation, thereby providing rapid access to indolines and quinolines.

Cobalt-Porphyrin-Catalyzed Intramolecular Buchner Reaction and Arene Cyclopropanation of In Situ Generated Alkyl Diazomethanes

Cobalt(II)-porphyrin catalyzed intramolecular Buchner reaction and arene cyclopropanation of alkyl diazomethanes generated in situ from N-tosylhydrazones gave a range of bicyclic cycloheptatriene fused pyrrolidines and tetracyclic cyclopropane fused pyrro

Efficient microwave-assisted synthesis of quinolines and dihydroquinolines under solvent-free conditions

A convenient and efficient procedure for the synthesis of quinolines and dihydroquinolines has been developed by a simple one-pot reaction of anilines with alkyl vinyl ketones on the surface of silica gel impregnated with indium(III) chloride under microwave irradiation without any solvent.

Microwave-assisted simple synthesis of quinolines from anilines and alkyl vinyl ketones on the surface of silica gel in the presence of indium(III) chloride

A simple and efficient procedure has been developed for the synthesis of 4-alkylquinolines by a one-pot reaction of anilines with alkyl vinyl ketones on the surface of silica gel impregnated with indium(III) chloride under microwave irradiation without any solvent.