401907-26-4Relevant articles and documents
Effect of TRPV1 Antagonist SC0030, a Potent Painkiller, on RANKL-mediated Osteoclast Differentiation Involved in Bone Resorption
More, Kunal N.,Lee, Yong-Jin,Kim, Kwang-Jin,Suh, Young-Ger,Son, Young-Jin,Chang, Dong-Jo
, p. 488 - 491 (2020/03/03)
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Novel non-vanilloid VR1 antagonist of high analgesic effects and its structural requirement for VR1 antagonistic effects
Suh, Young-Ger,Lee, Yong-Sil,Min, Kyung-Hoon,Park, Ok-Hui,Seung, Ho-Sun,Kim, Hee-Doo,Park, Hyoung-Geun,Choi, Ji-Yeon,Lee, Jeewoo,Kang, Sang-Wook,Oh, Uh-Taek,Koo, Jae-Yeon,Joo, Yung-Hyup,Kim, Sun-Young,Kim, Jin Kwan,Park, Young-Ho
, p. 4389 - 4393 (2007/10/03)
A novel non-vanilloid VR1 antagonist consisting of a new vanilloid equivalent exhibits excellent analgesic effects as well as highly potent antagonistic activities in both capsaicin single channel and calcium uptake assays. In addition, the structural requirement for the vanilloid equivalent of the potent VR1 antagonist has also been elucidated.