565448-36-4

Basic information

• Product Name: 3-fluoro-4-(MethylsulfonylaMino)benzylaMine
• Synonyms: 3-fluoro-4-(MethylsulfonylaMino)benzylaMine
• CAS NO: 565448-36-4
• Molecular Formula: C₈H₁₁FN₂O₂S
• Molecular Weight: 218.2485432
• Mol File: 565448-36-4.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-fluoro-4-(MethylsulfonylaMino)benzylaMine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-fluoro-4-(MethylsulfonylaMino)benzylaMine(565448-36-4)
• EPA Substance Registry System: 3-fluoro-4-(MethylsulfonylaMino)benzylaMine(565448-36-4)

Safety Data

• Hazardous Substances Data: 565448-36-4(Hazardous Substances Data)

Upstream product

• 452-80-2 2-fluoro-4-methylaniline 
• 702685-74-3 N-(2-fluoro-4-methylphenyl)benzamide 
• 40052-13-9 mono-tert-butyl malonate 
• 401909-16-8 N-(2-fluoro-4-cyanophenyl)methanesulfonamide 
• 143937-74-0 2-fluoro-4-iodo-1-methanesulfonylaminobenzene 
• 29632-74-4 2-fluro-4-iodoaniline 

Downstream Products

• 1207960-96-0 N-(2-fluoro-4-[3-(4-trimethylsilanylbenzyl)thioureidomethyl]phenyl)methanesulfonamide 
• 1375102-88-7 C₂₇H₃₈FN₃O₄S₂ 
• 1375102-78-5 C₂₆H₃₆FN₃O₄S₂ 
• 1375102-69-4 C₂₈H₄₀FN₃O₄S₂ 
• 1375102-68-3 C₂₆H₃₆FN₃O₄S₂ 
• 401907-26-4 1-(4-t-butylbenzyl)-3-(3-fluoro-4-methanesulfonylaminobenzyl)thiourea 

Relevant articles and documents

Asymmetric synthesis and receptor activity of chiral simplified resiniferatoxin (sRTX) analogues as transient receptor potential vanilloid 1 (TRPV1) ligands

The chiral isomers of the two potent simplified RTX-based vanilloids, compounds 2 and 3, were synthesized employing highly enantioselective PTC alkylation and evaluated as hTRPV1 ligands. The analysis indicated that the R-isomer was the eutomer in binding affinity and functional activity. The agonism of compound 2R was comparable to that of RTX. Docking analysis of the chiral isomers of 3 suggested the basis for its stereospecific activity and the binding mode of 3R.

TRPV1 ANTAGONISTS

Disclosed herein are compounds of formula (I) or pharmaceutically acceptable salts, prodrugs, or combinations thereof, wherein X1, L, Rx, Ry, Rz, R1, R2, A, m, n, p, q, and r are defined in

PENTAFLUOROSULPHANYL-SUBSTITUTED COMPOUND AND ITS USE FOR PRODUCING MEDICAMENTS

The present invention relates to pentafluorosulphanyl-substituted compounds, processes for preparing them, medicaments comprising these compounds, and the use of these compounds for producing medicaments.