402476-17-9

Upstream product

• 38274-16-7 2-bromo-1-(trimethylsilylethynyl)benzene 
• 122334-36-5 N-methoxy-N,4-dimethylbenzamide 
• 6630-33-7 ortho-bromobenzaldehyde 
• 1066-54-2 trimethylsilylacetylene 
• 77123-58-1 2-[2-(trimethylsilyl)ethynyl]benzaldehyde 
• 107624-39-5 2-iodophenyl 4-methylphenyl ketone 
• 106-38-7 para-bromotoluene 
• 133776-41-7 anthranilic acid N-methoxy-N-methylamide 

Downstream Products

• 402476-18-0 1-[1-(p-tolyl)ethenyl]-2-[(trimethylsilyl)ethynyl]benzene 
• 402475-95-0 1-(iodoethynyl)-2-[1-(p-tolyl)ethenyl]benzene 
• 402475-98-3 1-(iodoethynyl)-2-[1-(p-tolyl)-1-propenyl]benzene 
• 402475-99-4 1-(iodoethynyl)-2-(1-methylethenyl)cyclohexene 
• 402476-19-1 1-ethynyl-2-[1-(p-tolyl)ethynyl]benzene 
• 402476-21-5 C₁₈H₁₆ 

Relevant academic research and scientific papers

Cu(I)-Catalyzed Coupling and Cycloisomerization of Diazo Compounds with Terminal Yne-Alkylidenecyclopropanes: Synthesis of Functionalized Cyclopenta[ b]naphthalene Derivatives

A Cu(I)-catalyzed coupling and cycloisomerization of diazo compounds with terminal yne-alkylidenecyclopropanes (ACPs) has been presented. This reaction starts from the formation of an allenic intermediate in the Cu(I)-catalyzed cross-coupling reaction of a diazo compound with terminal alkyne in yne-tethered ACP and then undergoes a domino cycloisomerization of a 6π-electrocyclization and cyclopropane ring-opening rearrangement to give functionalized cyclopenta[b]naphthalene derivatives in moderate to excellent yields under mild conditions.

Indium(III)-Catalyzed Cyclization of Aromatic 5-Enynamides: Facile Synthesis of 2-Aminonaphthalenes, 2-Amino-1H-indenes, and 2,3-Dihydro-1H-indeno[2,1-b]pyridines

Indium(III)-catalyzed cyclization reactions of aromatic 5-enynamides were studied. Indium triflate enabled the efficient synthesis of 2-aminonaphthalenes and 2-amino-1H-indenes from aromatic N-methyl-N-tosyl-ynamides bearing an ortho-vinyl and -isobutenyl group, respectively. The aromatic N-3-arylpropargylynamides bearing an ortho-gem-dihalovinyl subunit underwent a tandem cyclization/carbobromination reaction in the presence of indium tribromide to provide the dibrominated 2,3-dihydro-1H-indeno[2,1-b]pyridine derivatives in good yields.

Reactions of iodinated vinylidene complexes generated from 1-Iodo-1-alkynes and W(CO)5(thf)

We have succeeded in generating iodinated tungsten vinylidene complexes from 1-iodo-1-alkynes and W(CO)5(thf), and have employed these complexes for two types of synthetically useful reactions, that is, 6π-electrocyclization for o-(iodoethynyl)