40297-26-5

Basic information

• Product Name: 2-(4-Chloro-phenyl)-cyclopentanone
• Synonyms: 2-(4-Chloro-phenyl)-cyclopentanone;2-(4-chlorophenyl)cyclopentan-1-one
• CAS NO: 40297-26-5
• Molecular Formula: C₁₁H₁₁ClO
• Molecular Weight: 194.65744
• Mol File: 40297-26-5.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-Chloro-phenyl)-cyclopentanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Chloro-phenyl)-cyclopentanone(40297-26-5)
• EPA Substance Registry System: 2-(4-Chloro-phenyl)-cyclopentanone(40297-26-5)

Safety Data

• Hazardous Substances Data: 40297-26-5(Hazardous Substances Data)

Usage

Structure

A cyclopentanone derivative with a 4-chlorophenyl group attached to the second carbon of the cyclopentanone ring.

Usage

A key intermediate in the synthesis of various pharmaceuticals, agrochemicals, and fine chemicals.

Common use

Commonly used as a building block for organic synthesis.

Versatility

Can undergo various chemical reactions to yield a wide range of derivatives with different physicochemical properties and biological activities.

Importance

Widely used in the pharmaceutical and chemical industries due to its versatility and importance as a synthetic intermediate.

Upstream product

• 106-39-8 bromochlorobenzene 
• 120-92-3 cyclopentanone 
• 5463-97-8 2-(1-hydroxycyclobutyl)-2-phenylacetic acid 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 78195-98-9 1-(4-chlorophenyl)cyclopentan-1-ol 
• 2371-98-4 1-(p-chlorophenyl)cyclopentene 

Downstream Products

• 1253111-93-1 (2S,3S)-2-(4-chlorophenyl)-2-(2-nitro-1-phenylethyl)cyclopentanone 
• 1263869-30-2 7-(4-chlorophenyl)-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione 
• 1263869-27-7 2,4-dichloro-7-(4-chlorophenyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidine 
• 1263869-31-3 2-chloro-7-(4-chlorophenyl)-N,N-dimethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine 
• 1263869-32-4 2-chloro-7-(4-chlorophenyl)-4-(3,3-difluoroazetidin-1-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidine 
• 1263869-33-5 2-chloro-7-(4-chlorophenyl)-N-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine 
• 1263869-29-9 7-(4-chlorophenyl)-6,7-dihydrocyclopenta[e][1,3]oxazine-2,4(3H,5H)-dione 
• 36978-49-1 4-(4-chlorobenzoyl)butanoic acid 
• 112607-05-3 δ-(p-chlorophenyl)-δ-valerolactone 
• 40297-27-6 2-(p-Chlorphenyl)-cyclopentanon-oxim 
• 112607-36-0 (+)-(S)-δ-(4-chlorophenyl)-δ-valerolactone 
• 1459806-94-0 C₁₁H₁₁ClO₂ 

Relevant articles and documents

Anodic oxidation triggered divergent 1,2- And 1,4-group transfer reactions of β-hydroxycarboxylic acids enabled by electrochemical regulation

We report a set of electrochemically regulated protocols for the divergent synthesis of ketones and β-keto esters from the same β-hydroxycarboxylic acid starting materials. Enabled by electrochemical control, the anodic oxidation of carboxylic acids proceeded in either a one-electron or a two-electron pathway, leading to a 1,4-aryl transfer or a semipinacol-type 1,2-group transfer product with excellent chemoselectivity. The 1,4-aryl transfer represents an unprecedented example of carbon-to-oxygen group transfer proceeding via a radical mechanism. In contrast to previously reported radical group transfer reactions, this 1,4-group transfer process features the migration of electron-rich aryl substituents. Furthermore, with these chemoselective electrochemical oxidation protocols, a range of ketones and β-keto esters including those possessing a challenging-to-access medium-sized ring could be synthesized in excellent yields. This journal is

Enantioselective Radical Ring-Opening Cyanation of Oxime Esters by Dual Photoredox and Copper Catalysis

Catalytic enantioselective chemical reactions involving highly reactive radical species remain largely unexplored. We report herein for the first time a novel enantioselective radical ring-opening cyanation of redox-active oxime esters by dual photoreodox

COMPOUNDS FOR THE REDUCTION OF β-AMYLOID PRODUCTION

The present disclosure provides a series of compounds of the formula (I), which modulate β-amyloid peptide (β-ΑΡ) production and are useful in the treatment of Alzheimer's Disease and other conditions affected by β-amyloid peptide (β-ΑΡ) production.