4033-88-9

Usage

Uses

Used in Organic Synthesis:
DIMETHYL 2-(4-NITROPHENYL)MALONATE is used as a reagent for its ability to undergo various chemical reactions, making it a valuable component in the synthesis of a wide array of organic compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, DIMETHYL 2-(4-NITROPHENYL)MALONATE is utilized as a reagent to aid in the development and analysis of new drug candidates, given its capacity for multiple types of chemical transformations.
Used in Chemical Research:
DIMETHYL 2-(4-NITROPHENYL)MALONATE is employed in academic and industrial chemical research settings to explore novel reactions and mechanisms, as well as to create new chemical entities for potential applications across various fields.

Upstream product

• 37434-59-6 dimethyl 2-phenylmalonate 
• 586-78-7 para-nitrophenyl bromide 
• 108-59-8 malonic acid dimethyl ester 
• 350-46-9 4-Fluoronitrobenzene 

Downstream Products

• 104-03-0 4-nitrobenzeneacetic acid 
• 131675-32-6 dimethyl 2-methyl-2-(4-nitrophenyl)malonate 
• 1006899-45-1 dimethyl 2-(4-aminophenyl)malonate hydrochloride 
• 675583-63-8 2-[2-(2-methoxyethoxy)ethyl]-2-(4-nitrophenyl)malonic acid dimethyl ester 
• 1402585-95-8 phenyl 4-(1,3-dihydroxy-2-methylpropan-2-yl)phenylcarbamate 
• 1236061-26-9 2-(4-aminophenyl)-2-methylpropane-1,3-diol 
• 29740-75-8 2-methyl-2-(4-nitrophenyl)propane-1,3-diol 
• 1402581-66-1 1-[[5-tert-butyl-2-(3-chlorophenyl)-2H-pyrazol-3-yl]methyl]-3-[4-[2-hydroxy-1-(hydroxymethyl)-1-methylethyl]phenyl]urea 
• 1402581-64-9 1-[[2-(3-chlorophenyl)-5-(trifluoromethyl)-2H-pyrazol-3-yl]methyl]-3-[4-[2-hydroxy-1-(hydroxymethyl)-1-methylethyl]phenyl]urea 
• 91748-03-7 1,3-dihydroxy-2-(4-nitrophenyl)propane 
• 3979-79-1 4-Acetamidophenyl-malonsaeure-diamid 
• 105535-09-9 1-(but-3-en-1-yl)-4-nitrobenzene 
• 28042-27-5 α-Methylene-4-nitrobenzeneacetic acid methyl ester 
• 3974-11-6 4-Acetamidophenyl-malonsaeure-dimethylester 

Relevant academic research and scientific papers

SUBSTITUTED PYRAZOLYL-BASED CARBOXAMIDE AND UREA DERIVATIVES BEARING A PHENYL MOIETY SUBSTITUTED WITH AN O-CONTAINING GROUP AS VANILLOID RECEPTOR LIGANDS

The invention relates to substituted pyrazolyl-based carboxamide and urea derivatives of formula (Q) as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

Arylaminoaryl-alkyl-substituted imidazolidine-2,4-diones, process for preparing them, medicaments comprising these compounds, and their use

This invention relates to arylaminoaryl-alkyl-substituted imidazolidone-2,4-diones of formula (I) and also to their physiologically tolerated salts: Wherein R, R′, R1 to R10, A, D, E, G, L and p are as defined herein. The invention also relates to processes for preparing them, pharmaceutical compositions comprising them and their therapeutic use. The compounds are suitable, for example, as anti-obesity drugs and for treating cardiometabolic syndrome.

Dimethyl malonate as a one-carbon source: A novel method of introducing carbon substituents onto aromatic nitro compounds

A number of carbon substituents possessing various functional groups could be introduced onto aromatic nitro compounds using dimethyl malonate as a one-carbon source and linker. Decarboxylation of both the ester groups originating from dimethyl malonate in this methodology is particularly significant.