40389-50-2

Basic information

• Product Name: α-Bromostilbene
• Synonyms: 1,1'-(1-Bromo-1,2-ethenediyl)bisbenzene;1,2-Diphenyl-1-bromoethene;α-Bromostilbene
• CAS NO: 40389-50-2
• Molecular Formula: C14H11Br
• Molecular Weight: 259.14
• Mol File: 40389-50-2.mol
• Article Data: 48

Chemical Properties

• Melting Point: 31 °C
• Boiling Point: 323.5±21.0 °C(Predicted)
• Appearance: /
• Density: 1.369±0.06 g/cm3(Predicted)
• CAS DataBase Reference: α-Bromostilbene(CAS DataBase Reference)
• NIST Chemistry Reference: α-Bromostilbene(40389-50-2)
• EPA Substance Registry System: α-Bromostilbene(40389-50-2)

Safety Data

• Hazardous Substances Data: 40389-50-2(Hazardous Substances Data)

Upstream product

• 618-32-6 Benzoyl bromide 
• 536-74-3 phenylacetylene 
• 62-53-3 aniline 
• 91-48-5 (E)-2,3-diphenylpropenoic acid 
• 123-11-5 4-methoxy-benzaldehyde 
• 186968-63-8 2-(Bromo-phenyl-methyl)-5,5-dimethyl-[1,3,2]dioxaphosphinane 2-oxide 
• 645-49-8 cis-stilben 
• 103-30-0 (E)-1,2-diphenyl-ethene 
• 501-65-5 diphenyl acetylene 
• 13440-24-9 anti-1,2-dibromo-1,2-diphenylethane 
• 13440-24-9 1,2-dibromo-1,2-diphenylethane 
• 91-47-4 (Z)-2,3-diphenylprop-2-enoic acid 
• 92161-01-8 (Z-1,2-diphenyl-2-bromovinyl)dibromoborane 
• 64-17-5 ethanol 

Downstream Products

• 54731-38-3 1,2-Diphenyl-1-dimethylsilyl-ethylen 
• 15022-93-2 Z-α-bromostilbene 
• 14447-41-7 (E)-1-bromo-1,2-diphenylethene 
• 19191-03-8 (E)-1-methoxy-1,2-diphenylethene 
• 19202-54-1 (Z)-1-methoxy-1,2-diphenylethene 
• 501-65-5 diphenyl acetylene 
• 103-30-0 (E)-1,2-diphenyl-ethene 
• 14285-68-8 decacarbonyldirhenium⁽⁰⁾ 
• 645-49-8 cis-stilben 
• 3947-92-0 1-deutero-cis-1,2-diphenylethylene 
• 35684-26-5 (E)-(ethene-1,2-diyl-1-d)dibenzene 
• 948-65-2 2-phenyl-indole 

Relevant articles and documents

Regio- and stereoselective synthesis of bromoalkenes by homolytic hydrobromination of alkynes with hydrogen bromide

Homolytic hydrobromination of terminal and internal alkynes with a commercially available solution of hydrogen bromide in acetic acid has been investigated for regio- and stereoselective synthesis of bromoalkenes. Under an aerobic atmosphere at room temperature, the reaction of ethynylarenes with a small excess of HBr efficiently gave (2-bromoethenyl)arenes with good to high E-selectivity. (Alk-1-ynyl)arenes, or internal alkynes bearing both phenyl and alkyl groups at the sp-carbons also underwent the air-initiated hydrobromination to exhibit high Z-selectivity under kinetic conditions using a half equivalent of HBr.

Regioselective Synthesis of α-Functional Stilbenes via Precise Control of Rapid cis- trans Isomerization in Flow

The rapid cis-trans isomerization of α-anionic stilbene was regioselectively controlled by using flow microreactors, and its reaction with various electrophiles was conducted. The reaction time was precisely controlled within milliseconds to seconds at -50 °C to selectively give the cis- or trans-isomer in high yields. This synthetic method in flow was well-applied to synthesize precursors of commercial drug compound, (E)- and (Z)-tamoxifen with high regioselectivity and productivity.

N -tert-butyl -2 -phenylindole derivative Preparation method and application

The invention belongs to the technical field of organic synthesis, and particularly relates to N - tert-butyl -2 -phenyl indole derivatives as well as a preparation method and application thereof. The preparation method comprises the following steps: (Z)-1 - bromo -1 - phenyl -2 - styrene derivative, N, N - di-tert-butyl diazepinone, palladium catalyst, monophosphine ligand, hydrocarbon activator, base and first solvent, and N -tert-butyl -2 -aryl indole derivatives which can synthesize substituent type diversity, and the prepared N -tert-butyl -2 -aryl indole derivative can be used for preparing biologically active molecules N -2 .