403990-79-4

Upstream product

• 3608-86-4 4-chloroacetylamino-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole 
• 90327-19-8 5-(1-(4-chlorophenoxy)ethyl)-4-phenyl-4H-1,2,4-triazole-3-thiol 
• 95262-84-3 2-(4-chlorophenoxy)propanoic acid methyl ester 
• 3307-39-9 2-(4-chlorophenoxy)propionic acid 
• 106-48-9 4-chloro-phenol 
• 52094-96-9 2-(4-chlorophenoxy)propionyl hydrazide 
• 90299-71-1 2-(2-(4-chlorophenoxy)propionyl)-N-phenylhydrazine thioformamide 
• 103-72-0 phenyl isothiocyanate 
• 83-07-8 4-amino-2,3-dimethyl-1-phenylpyrazolin-5-one 

Relevant academic research and scientific papers

Anti-hepatic fibrosis compound, preparation, preparation method and application

The invention belongs to the technical field of medicines, in particular to an anti-hepatic fibrosis compound, a preparation, a preparation method and application, and the structural formula of the anti-hepatic fibrosis compound is shown in the specification. The anti-hepatic fibrosis compound can obviously improve hepatic fibrosis, improve liver function indexes, reduce extracellular matrix accumulation of collagen and the like in extracellular interstitial substances, reduce the degree of hepatic fibrosis and inhibit the formation and development of hepatic fibrosis.

Anti-hepatic fibrosis compound and preparation as well as preparation method and application of compound

The invention belongs to the technical field of medicines, and in particular relates to an anti-hepatic fibrosis compound and a preparation as well as a preparation method and application of the compound. A structural formula of the anti-hepatic fibrosis compound is shown in the specification. The anti-hepatic fibrosis compound can obviously improve hepatic fibrosis, improve liver function indexes, reduce accumulation of extracellular matrixes such as collagen in extracellular interstitial substances, reduce the degree of the hepatic fibrosis and inhibit the formation and development of the hepatic fibrosis.

Synthesis of some triazolyl-antipyrine derivatives and investigation of analgesic activity

The synthesis of some triazolyl-antipyrine derivatives starting from 4-chloroacetamidoantipyrine and 3-(aryloxyalkyl)-4-ethyl/phenyl-5-mercapto-1,2,4-triazoles is described. The chemical structures of the compounds were elucidated by IR, 1H-NMR and mass spectral studies. These compounds were tested for analgesic activity.