404-51-3 Usage
Uses
Used in Pharmaceutical Industry:
1-(4-Chlorophenyl)-3-(4-fluorophenyl)urea, 97% is used as a pharmaceutical intermediate for the synthesis of various drugs. Its unique structure with a 4-chlorophenyl and a 4-fluorophenyl group allows for the development of new therapeutic agents with potential applications in treating various diseases.
Used in Agrochemical Industry:
In the agrochemical industry, 1-(4-Chlorophenyl)-3-(4-fluorophenyl)urea, 97% is used as a precursor for the synthesis of herbicides and pesticides. Its chemical properties enable the creation of effective compounds that can control the growth of unwanted plants and protect crops from pests.
Used in Material Science:
1-(4-Chlorophenyl)-3-(4-fluorophenyl)urea, 97% is utilized in material science for the development of new materials with specific properties. Its unique structure can contribute to the creation of materials with improved characteristics, such as enhanced stability, reactivity, or selectivity, for use in various applications.
Overall, 1-(4-Chlorophenyl)-3-(4-fluorophenyl)urea, 97% is a versatile chemical compound with a wide range of applications across different industries, thanks to its high purity and unique structural features.
Check Digit Verification of cas no
The CAS Registry Mumber 404-51-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,0 and 4 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 404-51:
(5*4)+(4*0)+(3*4)+(2*5)+(1*1)=43
43 % 10 = 3
So 404-51-3 is a valid CAS Registry Number.
InChI:InChI=1/C13H10ClFN2O/c14-9-1-5-11(6-2-9)16-13(18)17-12-7-3-10(15)4-8-12/h1-8H,(H2,16,17,18)
404-51-3Relevant academic research and scientific papers
COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER
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Paragraph 0245, (2020/07/08)
This disclosure relates to compounds, pharmaceutical compositions comprising them, and methods of using the compounds and compositions for treating diseases related to Heat Shock Transcription Factor 1 (HSF1) activity and/or function. More particularly, this disclosure relates to methods of inhibiting HSF1 activity with these compounds and pharmaceutical compositions thereof, and methods of treating diseases associated with HSF1 activity and/or function, such as cancer.
A Palladium-Catalyzed Domino Procedure for the Synthesis of Unsymmetrical Ureas
Chen, Bo,Peng, Jin-Bao,Ying, Jun,Qi, Xinxin,Wu, Xiao-Feng
supporting information, p. 2820 - 2824 (2018/08/17)
A palladium-catalyzed carbonylative procedure for the synthesis of unsymmetrical ureas has been developed. This one-pot one-step cascade procedure is consisted by three individual processes: carbonylation, Curtius rearrangement, and nucleophilic addition. A series of unsymmetrical ureas were prepared from easily available aryl iodides and amines in moderate to excellent yields. This procedure provides a convenient and practical approach for unsymmetrical urea synthesis. (Figure presented.).
