40503-94-4

Basic information

• Product Name: 4-(4-(TRIFLUOROMETHYL)PHENYL)CYCLOHEXANONE
• Synonyms: 4-(4-(TRIFLUOROMETHYL)PHENYL)CYCLOHEXANONE;4-[4-(trifluoromethyl)phenyl]cyclohexan-1-one
• CAS NO: 40503-94-4
• Molecular Formula: C₁₃H₁₃F₃O
• Molecular Weight: 242.239
• Mol File: 40503-94-4.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(4-(TRIFLUOROMETHYL)PHENYL)CYCLOHEXANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-(TRIFLUOROMETHYL)PHENYL)CYCLOHEXANONE(40503-94-4)
• EPA Substance Registry System: 4-(4-(TRIFLUOROMETHYL)PHENYL)CYCLOHEXANONE(40503-94-4)

Safety Data

• Hazardous Substances Data: 40503-94-4(Hazardous Substances Data)

Upstream product

• 402-51-7 4-(trifluoromethyl)phenylmagnesium bromide 
• 680596-79-6 4,4,5,5-tetramethyl-2-(1,4-dioxaspiro[4.5]dec-7-en-8-yl)-1,3,2-dioxaborolane 
• 402-43-7 p-trifluoromethylphenyl bromide 
• 4746-97-8 cyclohexanedione monoethylene ketal 
• 36716-72-0 4-[4-(Trifluoromethyl)phenyl]-4-hydroxycyclohexanone 

Downstream Products

• 1254342-83-0 (S)-5,7-dibromo-2-(4-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydroacridine 

Relevant articles and documents

Desymmetrizing Isomerization of Alkene via Thiazolinyl Iminoquinoline Cobalt Catalysis

We report a cobalt-catalyzed desymmetrizing isomerization of exo-cyclic alkenes to generate chiral 1-methylcyclohexene derivatives with good yields and enantioselectivities. A novel chiral thiazolinyl iminoquinoline ligand and its cobalt complex were desi

GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with a defect in glyoxylate metabolism, for example a disease or disorder associated with the enzyme glycolate oxidase (GO) or alterations in oxalate metabolism. Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.

Enantioselective Synthesis of Chiral Oxime Ethers: Desymmetrization and Dynamic Kinetic Resolution of Substituted Cyclohexanones

Axially chiral cyclohexylidene oxime ethers exhibit unique chirality because of the restricted rotation of C=N. The first catalytic enantioselective synthesis of novel axially chiral cyclohexylidene oximes has been developed by catalytic desymmetrization of 4-substituted cyclohexanones with O-arylhydroxylamines and is catalyzed by a chiral BINOL-derived strontium phosphate with excellent yields and good enantioselectivities. In addition, chiral BINOL-derived phosphoric acid catalyzed dynamic kinetic resolution of α-substituted cyclohexanones has been performed and yields versatile intermediates in high yields and enantioselectivities.