40515-82-0

Basic information

• Product Name: Quinoline, 2-phenoxy-
• CAS NO: 40515-82-0
• Molecular Formula: C15H11NO
• Molecular Weight: 221.258
• Mol File: 40515-82-0.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Quinoline, 2-phenoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Quinoline, 2-phenoxy-(40515-82-0)
• EPA Substance Registry System: Quinoline, 2-phenoxy-(40515-82-0)

Safety Data

• Hazardous Substances Data: 40515-82-0(Hazardous Substances Data)

Upstream product

• 59-31-4 2-quinolone 
• 1613-37-2 Quinoline N-oxide 
• 108-95-2 phenol 
• 93-10-7 quinoline-2-carboxylic acid 
• 59-31-4 2-hydroxyquinoline 
• 73568-25-9 2-chloro-3-quinoline carboxaldehyde 
• 612-62-4 2-Chloroquinoline 
• 36439-44-8 tetramethylammonium phenoxide 
• 115-86-6 phosphoric acid triphenyl ester 
• 139-02-6 sodium phenoxide 

Downstream Products

• 612-96-4 2-Phenylquinoline 
• 67176-94-7 1-phenyl-1,2-dihydro-2-quinolone 
• 59-31-4 2-quinolone 
• 108-95-2 phenol 
• 1415226-45-7 1-amino-3-(2-phenoxyquinolin-3-yl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile 

Relevant articles and documents

Substituent Effects of 2-Pyridones on Selective O-Arylation with Diaryliodonium Salts: Synthesis of 2-Aryloxypyridines under Transition-Metal-Free Conditions

An efficient transition-metal-free strategy to synthesize 2-aryloxypyridine derivatives has been developed by a selective O-arylation of 2-pyridones with diaryliodonium salts. The reaction was compatible with a series of functional groups for 2-pyridones and diaryliodonium salts such as halides, nitro, cyano, and ester groups. The substituents at the C6-position of 2-pyridones favored O-arylation products because of steric hindrance. The reaction was easily performed on a gram-scale and 6-chloro-2-pyridone was a good precursor to access various unsubstituted 2-aryloxypyridines by dehalogenation. A P2Y 1 lead compound analogue could be prepared in good yield over two steps.

A Direct C2-Selective Phenoxylation and Alkoxylation of Quinoline N-Oxides with Various Phenols and Alcohols in the Presence of H-Phosphonate

A practical and efficient method for the synthesis of 2-aroxy(alkoxy)quinolines has been developed by direct cross-dehydrogenative coupling reaction between quinoline N-oxides and readily available phenols and alcohols in the presence of H-phosphonate and

A counteranion triggered arylation strategy using diaryliodonium fluorides

A mild and transition metal-free counteranion triggered arylation strategy has been developed using diaryliodonium fluorides. The fluoride counteranion within the hypervalent iodonium species displays unusual reactivity that activates a phenolic O-H bond leading to electrophilic O-arylation. A wide range of phenols and diaryliodonium salts are compatible with this transformation under remarkably mild conditions. Furthermore, we pre-empt the wider implications of this strategy by demonstrating the compatibility of the arylation tactic with latent carbon nucleophiles.