4057-62-9

Basic information

• Product Name: 1,2,5-Thiadiazole, 3-phenyl-
• CAS NO: 4057-62-9
• Molecular Formula: C8H6N2S
• Molecular Weight: 162.215
• Mol File: 4057-62-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1,2,5-Thiadiazole, 3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,5-Thiadiazole, 3-phenyl-(4057-62-9)
• EPA Substance Registry System: 1,2,5-Thiadiazole, 3-phenyl-(4057-62-9)

Safety Data

• Hazardous Substances Data: 4057-62-9(Hazardous Substances Data)

Usage

Type of compound

Heterocyclic compound

Structure

Five-membered ring consisting of three carbon atoms, one nitrogen atom, and one sulfur atom

Substituent

3-phenyl group

Potential applications

a. Pharmaceuticals
b. Agrochemicals

Biological activities

a. Antimicrobial
b. Antifungal
c. Anticancer

Use in organic synthesis

Building block for creating new molecules for various industries

Other applications

a. Corrosion inhibitor
b. Catalyst in chemical reactions

Upstream product

• 5700-56-1 1,2-diaminophenylethane 
• 288-39-1 1,2,5-thiadiazole 
• 21572-32-7 2-chloro-1-phenyl-ethanone oxime 
• 536-74-3 phenylacetylene 
• 10341-75-0 (E)-1-phenylethanone oxime 
• 50314-86-8 acetophenone oxime 
• 14181-72-7 2-bromo-1-phenyl-ethanone oxime 

Downstream Products

• 25283-73-2 3-Methyl-4-phenyl-1,2,5-thiadiazole 
• 106353-38-2 3-Phenyl-4-vinyl-[1,2,5]thiadiazole 
• 64109-11-1 3-phenyl-[1,2,5]selenadiazole 
• 56792-18-8 3-methyl-4-phenyl-1,2,5-selenadiazole 
• 74-93-1 methylthiol 
• 75-18-3 dimethylsulfide 
• 4057-61-8 3,4-diphenyl-1,2,5-thiadiazole 
• 352-93-2 diethyl sulphide 
• 112633-36-0 3-ethyl-4-phenyl-1,2,5-selenadiazole 
• 75-08-1 ethanethiol 

Relevant articles and documents

Reactions of Monohalomethyl Aryl Ketoximes with Tetrasulfur Tetranitride: Much Improved Synthesis of 3-Aryl-1,2,5-thiadiazoles

Reactions of chloromethyl aryl ketoximes (1, X = Cl) with tetrasulfur tetranitride in p-dioxane at reflux for 4 h afforded 3-aryl-1,2,5-thiadiazoles (2) in 37-92percent yields, whereas those of bromo analogs under the same conditions gave 2 and 3-aryl-4-bromo-1,2,5-thiadiazoles 3 in 48-81percent and 17-31percent yields, respectively.However, the compounds (3) were not formed in the presence of pyridine. α-Nitrosostyrene and its ring-substituted derivatives (4) are proposed as intermediates for the formations of 2.

Organic Heterocyclothiazenes. Part 2. Reaction of Tetrasulphur Tetranitride with Phenylacetylene and Diphenylacetylene

The reaction of S4N4 with diphenylacetylene in boiling toluene has been found to give 3,4-diphenyl-1,2,5-thiadiazole (1) as the major product and 3,5-diphenyl-1,4,2,6-dithiadiazine (4), a new heterocyclic system, as a minor product.The same reaction with

Reactions of Tetrasulphur Tetranitride with Alkynes; 1,4,2,6-Dithiadiazines and 1,3,2-Dithiazoles

Reaction of S4N4 with diphenylacetylene and phenylacetylene gives two new, thermally stable heterocyclic systems, the 1,4,2,6-dithiadiazine (3) and the 1,3,2-dithiazolylimine (7), respectively, as minor products; these structures, determined by X-ray diff