4057-62-9

Usage

Type of compound

Heterocyclic compound

Structure

Five-membered ring consisting of three carbon atoms, one nitrogen atom, and one sulfur atom

Substituent

3-phenyl group

Potential applications

a. Pharmaceuticals
b. Agrochemicals

Biological activities

a. Antimicrobial
b. Antifungal
c. Anticancer

Use in organic synthesis

Building block for creating new molecules for various industries

Other applications

a. Corrosion inhibitor
b. Catalyst in chemical reactions

Upstream product

• 536-74-3 phenylacetylene 
• 5700-56-1 1,2-diaminophenylethane 
• 14181-72-7 2-bromo-1-phenyl-ethanone oxime 
• 21572-32-7 2-chloro-1-phenyl-ethanone oxime 
• 288-39-1 1,2,5-thiadiazole 
• 10341-75-0 (E)-1-phenylethanone oxime 
• 50314-86-8 acetophenone oxime 

Downstream Products

• 64109-11-1 3-phenyl-[1,2,5]selenadiazole 
• 56792-18-8 3-methyl-4-phenyl-1,2,5-selenadiazole 
• 74-93-1 methylthiol 
• 75-18-3 dimethylsulfide 
• 25283-73-2 3-Methyl-4-phenyl-1,2,5-thiadiazole 
• 106353-38-2 3-Phenyl-4-vinyl-[1,2,5]thiadiazole 
• 352-93-2 diethyl sulphide 
• 112633-36-0 3-ethyl-4-phenyl-1,2,5-selenadiazole 
• 75-08-1 ethanethiol 
• 4057-61-8 3,4-diphenyl-1,2,5-thiadiazole 

Relevant academic research and scientific papers

Reactions of Monohalomethyl Aryl Ketoximes with Tetrasulfur Tetranitride: Much Improved Synthesis of 3-Aryl-1,2,5-thiadiazoles

Reactions of chloromethyl aryl ketoximes (1, X = Cl) with tetrasulfur tetranitride in p-dioxane at reflux for 4 h afforded 3-aryl-1,2,5-thiadiazoles (2) in 37-92percent yields, whereas those of bromo analogs under the same conditions gave 2 and 3-aryl-4-bromo-1,2,5-thiadiazoles 3 in 48-81percent and 17-31percent yields, respectively.However, the compounds (3) were not formed in the presence of pyridine. α-Nitrosostyrene and its ring-substituted derivatives (4) are proposed as intermediates for the formations of 2.

Reactions of Tetrasulfur Tetranitride with Alkyl Aryl Ketoximes: Synthesis of 3-Aryl- and 3-Alkyl-4-aryl-1,2,5-thiadiazoles

Tetrasulfur tetranitride (S4N4) was treated with various alkyl aryl ketoximes having two hydrogens at the α-carbon atom to the oxime functionality in p-dioxane at reflux to give 3-substituted and 3,4-disubstituted 1,2,5-thiadiazoles in moderate yields.Rea

Organic Heterocyclothiazenes. Part 2. Reaction of Tetrasulphur Tetranitride with Phenylacetylene and Diphenylacetylene

The reaction of S4N4 with diphenylacetylene in boiling toluene has been found to give 3,4-diphenyl-1,2,5-thiadiazole (1) as the major product and 3,5-diphenyl-1,4,2,6-dithiadiazine (4), a new heterocyclic system, as a minor product.The same reaction with

Reactions of Tetrasulphur Tetranitride with Alkynes; 1,4,2,6-Dithiadiazines and 1,3,2-Dithiazoles

Reaction of S4N4 with diphenylacetylene and phenylacetylene gives two new, thermally stable heterocyclic systems, the 1,4,2,6-dithiadiazine (3) and the 1,3,2-dithiazolylimine (7), respectively, as minor products; these structures, determined by X-ray diff