406-81-5

Usage

Uses

1-Bromo-4,4,4-trifluorobutane is used as pharmaceutical intermediate.

InChI:InChI=1/C4H6BrF3/c5-3-1-2-4(6,7)8/h1-3H2

Upstream product

• 461-18-7 4,4,4-trifluorobutanol 

Downstream Products

• 352-61-4 5,5,5-trifluoro-1-pentanol 
• 1027051-93-9 3-[3-(4,4,4-Trifluoro-butoxy)-phenyl]-propionic acid ethyl ester 
• 260045-98-5 (2-chloro-pyrimidin-4-yl)-(2,5-dichloro-phenyl)-(4,4,4-trifluoro-butyl)-amine 
• 675847-66-2 2-methyl-4-{2-[4-(4,4,4-trifluoro-butoxy)-phenyl]-ethyl}-4,5-dihydro-oxazol-4-yl-methanol 
• 1413947-89-3 methyl 4-(4,4,4-trifluoro-butoxy)-benzoate 
• 260054-34-0 4-Chloro-6-[N-(4,4,4-trifluorobutyl)-2-chloro-5-methylanilino]pyrimidine 
• 209986-66-3 3-(benzoxycarbonyl)amino-2,3-dihydro-1-(4,4,4-trifluorobutyl)-5-phenyl-1H-1,4-benzodiazepin-2-one 
• 185835-97-6 SL25.1188 
• 108-95-2 phenol 
• 1034355-04-8 5-chloro-N-[(2Z)-5,5-dimethyl-3-(4,4,4-trifluorobutyl)-1,3-thiazolidin-2-ylidene]-2-methoxybenzamide 
• 912949-83-8 1-(1-Ethyl-propyl)-3-{3-methoxy-4-[4-(4,4,4-trifluoro-butylamino)-phenoxy]-phenyl}-urea 
• 1133166-31-0 C₂₈H₄₂F₃N₆O₁₀P 
• 1240300-20-2 6-{4-[4-(4,4,4-trifluorobutoxy)phenyl]piperidin-1-yl}-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine 
• 1253585-20-4 5-[2,4-dihydroxy-6-(4-nitrophenoxy)phenyl]-N-[1-(4,4,4-trifluorobutyl)piperidin-4-yl]isoxazole-3-carboxamide 

Relevant academic research and scientific papers

Pyrazolo[3,4-b]pyridine carboxylic acid esters and their pharmaceutical use

Compounds of the formula (I): STR1 wherein R1, R3, R4, R5 and R6 have defined values and the N-oxides at the 7-position of the pyrazolo[3,4-b]pyridine ring system and the pharmaceutically-acceptable acid-addition salts thereof, processes for their preparation and use, pharmaceutical compositions, and intermediates for preparing said compounds of the formula (I). The compounds of formula (I) are central nervous system depressants, for example anxiolytic agents.