40610-41-1

Usage

Uses

Used in Pharmaceutical Industry:
IMp. K (EP) is used as an impurity in the production of Ampicillin (A634300) for the following reasons:
1. As a β-lactam antibiotic, Ampicillin is effective in treating a wide range of bacterial infections, making it a crucial component in the pharmaceutical industry.
2. The presence of IMp. K (EP) as an impurity in Ampicillin may affect the drug's efficacy, safety, and quality. Therefore, it is essential to monitor and control the levels of this impurity during the manufacturing process to ensure the drug meets the required standards.

Upstream product

• 875-74-1 (R)-phenylglycine 
• 3282-30-2 pivaloyl chloride 
• 2835-06-5 phenylglycin 
• 292638-85-8 acrylic acid methyl ester 
• 60050-53-5 2-phenyl-2-pivalamidoacetic acid 
• 100-42-5 styrene 

Downstream Products

• 1420293-77-1 C₁₃H₁₆NO₃^(1-)*C₁₆H₃₆N⁽¹⁺⁾ 

Relevant academic research and scientific papers

Enantioselective C-H Olefination of α-Hydroxy and α-Amino Phenylacetic Acids by Kinetic Resolution

Significant progress has been made in the past decade regarding the development of enantioselective C-H activation reactions by desymmetrization. However, the requirement for the presence of two chemically identical prochiral C-H bonds represents an inherent limitation in scope. Reported is the first example of kinetic resolution by a palladium(II)-catalyzed enantioselective C-H activation and C-C bond formation, thus significantly expanding the scope of enantioselective C-H activation reactions.

Synthesis and enantiomeric recognition studies of a novel 5,5-dioxophenothiazine-1,9 bis(thiourea) containing glucopyranosyl groups

A novel optically active 5,5-dioxophenothiazine-1,9 bis(thiourea) containing glucopyranosyl groups was synthesized and its enantiomeric recognition properties were examined towards the enantiomers of tetrabutylammonium salts of chiral α-hydroxy and N-protected α-amino acids using UV-vis spectroscopy.