60050-53-5

Basic information

• Product Name: 2-phenyl-2-pivalamidoacetic acid
• Synonyms: 2-phenyl-2-pivalamidoacetic acid
• CAS NO: 60050-53-5
• Molecular Weight: 235.283
• Mol File: 60050-53-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-phenyl-2-pivalamidoacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-2-pivalamidoacetic acid(60050-53-5)
• EPA Substance Registry System: 2-phenyl-2-pivalamidoacetic acid(60050-53-5)

Safety Data

• Hazardous Substances Data: 60050-53-5(Hazardous Substances Data)

Upstream product

• 124-38-9 carbon dioxide 
• 26209-45-0 N-benzyl-2,2-dimethylpropanamide 
• 3282-30-2 pivaloyl chloride 
• 2835-06-5 phenylglycin 

Downstream Products

• 59990-70-4 2-(tert-butyl)-4-phenyl-1,3-oxazol-5(4H)-on 
• 915280-39-6 (2S)-[(2,2-dimethylpropanoyl)amino](phenyl)acetic acid 
• 40610-41-1 (2R)-[(2,2-dimethylpropanoyl)amino](phenyl)acetic acid 
• 120226-40-6 N-Pivaloyl-DL-phenylglycin-methylester 

Relevant articles and documents

Enantioselective C-H Olefination of α-Hydroxy and α-Amino Phenylacetic Acids by Kinetic Resolution

Significant progress has been made in the past decade regarding the development of enantioselective C-H activation reactions by desymmetrization. However, the requirement for the presence of two chemically identical prochiral C-H bonds represents an inherent limitation in scope. Reported is the first example of kinetic resolution by a palladium(II)-catalyzed enantioselective C-H activation and C-C bond formation, thus significantly expanding the scope of enantioselective C-H activation reactions.