40688-79-7

Usage

Chlorinated derivative

Based on its molecular formula, 2-(3-trifluoromethylphenoxy)-3-pyridinecarboxylic acid chloride is a chlorinated version of 2-(3-trifluoromethylphenoxy)-nicotinic acid.

Synthesis in pharmaceuticals and agrochemicals

The chloride form of 2-(3-trifluoromethylphenoxy)-3-pyridinecarboxylic acid chloride is commonly used in the synthesis of pharmaceuticals and agrochemicals due to its reactive nature.

Potential applications in drug development

2-(3-trifluoromethylphenoxy)-3-pyridinecarboxylic acid chloride has potential applications in the development of drugs for various conditions, making it a valuable compound for the pharmaceutical industry.

Production of agricultural chemicals

2-(3-trifluoromethylphenoxy)-3-pyridinecarboxylic acid chloride is also used in the production of agricultural chemicals, such as pesticides and crop protection products, contributing to the agricultural industry.

Importance for pharmaceutical and agricultural industries

The specific properties and uses of 2-(3-trifluoromethylphenoxy)-3-pyridinecarboxylic acid chloride make it an important compound for both the pharmaceutical and agricultural industries.

Upstream product

• 98-17-9 3-Trifluoromethylphenol 
• 2942-59-8 2-chloronicotinic acid 
• 36701-89-0 2-(3-Trifluoromethyl-phenoxy)-nicotinic acid 

Relevant academic research and scientific papers

Design, Synthesis, and Herbicidal Activity of Novel Diphenyl Ether Derivatives Containing Fast Degrading Tetrahydrophthalimide

To seek new protoporphyrinogen oxidase (PPO) inhibitors with better biological activity, a series of novel diphenyl ether derivatives containing tetrahydrophthalimide were designed based on the principle of substructure splicing and bioisomerization. PPO inhibition experiments exhibited that 6c is the most potential compound, with the half-maximal inhibitory concentration (IC50) value of 0.00667 mg/L, showing 7 times higher activity than Oxyfluorfen (IC50 = 0.0426 mg/L) against maize PPO and similar herbicidal activities to Oxyfluorfen in weeding experiments in greenhouses and field weeding experiments. In view of the inspected bioactivities, the structure-activity relationship (SAR) of this series of compounds was also discussed. Crop selection experiments demonstrate that compound 6c is safe for soybeans, maize, rice, peanuts, and cotton at a dose of 300 g ai/ha. Accumulation analysis experiments showed that the accumulation of 6c in some crops (soybeans, peanuts, and cotton) was significantly lower than Oxyfluorfen. Current work suggests that compound 6c may be developed as a new herbicide candidate in fields.

N-substituted, 2-phenoxynicotinamide compounds and the herbicidal use thereof

This invention relates to novel herbicidal compounds having the formula STR1 in which X is chloro, bromo, trifluoromethyl, methyl or ethyl; R1 is hydrogen or C3 -C5 alkenyl; and R2 is (a) C3 -C5