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Usage

Uses

Used in Cosmetics and Personal Care Products:
2,4-dimethyl-6-phenyl-1,3-dioxane is used as a fragrance ingredient for its pleasant scent, enhancing the sensory appeal of cosmetics and personal care products.
Used in Pharmaceuticals and Medical Applications:
2,4-dimethyl-6-phenyl-1,3-dioxane is utilized for its antiseptic and disinfectant properties, contributing to the effectiveness of pharmaceuticals and medical treatments.
Used in Chemical Synthesis:
2,4-dimethyl-6-phenyl-1,3-dioxane is used as a chemical intermediate in the production of other compounds, such as pharmaceuticals, dyes, and agricultural chemicals, playing a crucial role in the synthesis of these substances.
Used in Industry:
2,4-dimethyl-6-phenyl-1,3-dioxane is used as a raw material in various industrial processes, where its chemical properties are harnessed to produce a range of products.

InChI:InChI=1/C12H16O2/c1-9-8-12(14-10(2)13-9)11-6-4-3-5-7-11/h3-7,9-10,12H,8H2,1-2H3

Upstream product

• 100-42-5 styrene 
• 75-07-0 acetaldehyde 
• 65469-88-7 1-phenylbutane-1,3-diol 
• 123-63-7 paracetaldehyde 
• 7647-01-0 hydrogenchloride 
• 34688-55-6 1,3-diacetoxy-1-phenyl-butane 

Relevant academic research and scientific papers

Highly efficient synthesis of 1,3-dioxanes via prins reaction in bronsted-acidic imidazolium ionic liquid

The high-yielding synthesis of a wide variety of 1,3-dioxanes via the Prins reaction under mild conditions has been demonstrated using Bronsted- acidic imidazolium ionic liquid [bmim(SO3H)][OTf] or bmimOTf. The use of ionic liquid makes this synthesis simple, convenient, cost-effective, and environmentally friendly. Furthermore, bmimOTf was conveniently separated from the products and can be easily recycled for the Prins reaction with excellent yields. This method works well with a variety of aliphatic aldehydes including formaldehyde, acetaldehyde, propionaldehyde, and cyclohexanecarboxaldehyde. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications for the following free supplemental resource(s): Full experimental and spectral details.]

Iodine as a mild and versatile reagent for the synthesis of 1,3-dioxane derivatives via the Prins reaction

Iodine is found to be an effective reagent for the cross-coupling of olefins with aldehydes under mild conditions to produce 4-substituted 1,3-dioxane derivatives in excellent yields and in short reaction times with high selectivity. The use of iodine makes this procedure simple, convenient, cost-effective and practical. This method works not only with formaldehyde but also with acetaldehyde, propionaldehyde and cyclohexanecarboxaldehyde.

Cation-Exchanged Montmorillonite (Mn+-Mont)-Catalyzed Prins Reaction

The Prins reaction of styrenes with paraformaldehyde or 1,3,5-trioxane in toluene in the presence of cation-exchanged montmorillonite (Mn+-mont), which worked as a Bronsted acid catalyst, at 80°C produced 4-aryl-1,3-dioxanes selectively in up to 99% isolated yield with a turnover number of up to 5.9×102. Among the examined 21 Mn+-monts, Ce3+- and Fe3+-monts were revealed to be quite effective. Regeneration of the catalyst was confirmed with the Ce3+-mont, which could be effectively recycled at least three times. Many lanthanide metal ion-exchanged montmorillonites (Ln3+-monts) were prepared and characterized by X-ray powder diffraction (XRD) and temperature-programmed desorption of ammonia gas (NH3-TPD) methods.

CONDENSATION D'ALCENES AROMATIQUES AVEC L'ACETALDEHYDE CATALYSEE PAR DES RESINES ECHANGEUSES D'IONS-II; STEREOISOMERISATION ET SYNTHESE DE NOUVEAUX DIOXA-1,3 CYCLOHEXANES POLYSUBSTITUES

The interconversion of the three stereoisomers of 4-anisyl-2,5,6 trimethyl-1,3 dioxacyclohexane, obtained from the condensation reaction between anethole and acetaldehyde, depends on the experimental conditions.In some cases, a reversal to the starting alkene could be observed: such a phenomenon does not seem to have been reported so far in the isomerization reactions of 1,3-dioxacyclohexanes.The data can be accounted for by a reaction mechanism involving various cationic intermediates.New 1,3-dioxacyclohexanes were obtained from acetaldehyde and various aromatic alkenes under mild reaction conditions in the presence of sulfonic ion-ex changers used as catalysts, in good yields and with high selectivity.