407-27-2Relevant academic research and scientific papers
The First Versatile and Practical Building Blocks Equivalent to the Synthon of Monofluoromethylene Dicarbanion
Takeuchi, Yoshio,Nagata, Kazuhiro,Koizumi, Toru
, p. 5061 - 5063 (2007/10/02)
New monofluorinated synthons have been prepared.The use of α-fluoro-α-nitro carboxylic esters as versatile building blocks was demonstrated by their conversion to various monofluorinated compounds via fluoromethyl anion and fluoromethylene dianion equivalents.
EFFET DE LA CONCENTRATION EN ACIDE FLUORHYDRIQUES DANS LA PYRIDINE SUR LA REGIO-SELECTITE DE LA FLUORATION PAR DEAMINATION D'α-AMINO-ESTERS : SYNTHESES DE COMPOSES CARBOXYLES-β-FLUORES.
Hamman, Sylvain,Beguin, Claude G.
, p. 57 - 60 (2007/10/02)
Fluorodeamination of α-amino-esters with sodium nitrite in HF-pyridine gives mainly β-fluoro-esters.The molar ratio HF-pyridine is the main parameter for the α-β regioselectivity.
Conformational Studies on 2-Fluoro-1,2-disubstituted Ethanes by NMR Spectroscopy. Influence of Electronegativity on Vicinal Proton-Proton and Fluorine-Proton Coupling Constants
Hamman, Sylvain,Beguin, Claude,Charlon, Claude,Luu-Duc, Cuong
, p. 361 - 366 (2007/10/02)
The analysis of the ABKX spectra of thirteen compounds of the series RC(H-K)(F-X)C(H-A)(H-B)X gave the four vicinal proton-proton and fluorine-proton coupling constants.These coupling constants of conformationally mobile structures were used (i) to calcul
