43101-48-0

Basic information

• Product Name: diethyl DL-aspartate
• Synonyms: diethyl DL-aspartate;(±)-Aspartic acid diethyl;DL-Aspartic acid diethyl;Aspartic acid, 1,4-diethyl ester;Aspartic acid, diethyl ester;Einecs 256-095-6
• CAS NO: 43101-48-0
• Molecular Formula: C₈H₁₅NO₄
• Molecular Weight: 189.209
• EINECS: 256-095-6
• Mol File: 43101-48-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 259.5°Cat760mmHg
• Flash Point: 97.5°C
• Appearance: /
• Density: 1.102g/cm³
• Solubility: Ethanol, Water
• PKA: 6.19±0.33(Predicted)
• CAS DataBase Reference: diethyl DL-aspartate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl DL-aspartate(43101-48-0)
• EPA Substance Registry System: diethyl DL-aspartate(43101-48-0)

Safety Data

• Hazardous Substances Data: 43101-48-0(Hazardous Substances Data)

Usage

Uses

Aspartic Acid Diethyl Ester is an intermediate in the synthesis of Aspartic Acid (A788955) related compounds.

InChI:InChI=1/C8H15NO4/c1-3-12-7(10)5-6(9)8(11)13-4-2/h6H,3-5,9H2,1-2H3/t6-/m0/s1

Upstream product

• 131401-52-0 Diethyl 2-(Hydroxyimino)succinate 
• 872822-56-5 nitroso-succinic acid diethyl ester 
• 110-17-8 (2E)-but-2-enedioic acid 
• 64-17-5 ethanol 
• 21860-86-6 aspartic acid 4-ethyl ester 
• 141-05-9 Diethyl maleate 
• 623-91-6 diethyl Fumarate 
• 7664-41-7 ammonia 
• 64-19-7 acetic acid 
• 617-45-8 aspartic Acid 

Downstream Products

• 71416-69-8 N-(1,2-bisethoxycarbonylethyl)-N'-(2-fluoro-4-chlorophenyl)-3,4,5,6-tetrahydrophthalamide 
• 407-27-2 2-Fluor-bernsteinsaeure-diethylester 
• 142784-76-7 diethyl 2-(dibenzylamino)succinate 
• 95361-46-9 C₁₄H₁₇NO₄S 
• 104830-35-5 p-toluenesulfonamidosuccinic acid diethyl ester 
• 862508-85-8 5-[(4-fluorophenyl)methyl]-2,3-pyridinecarboxylic acid 
• 50838-94-3 (2,4-dinitro-phenylhydrazono)-succinic acid diethyl ester 
• 1057404-70-2 dl-N-(1,4-dioxo-4-phenylbutyl)aspartic acid diethyl ester 
• 2058-58-4 (R)-Asparagine 
• 70-47-3 L-asparagine 
• 617-45-8 aspartic Acid 
• 111472-02-7 (2-phenyl-1⁽³⁾H-imidazol-4-yl)-acetic acid ethyl ester 
• 13552-87-9 L-aspartic acid diethyl ester 
• 3130-87-8 ASPARAGINE 

Relevant articles and documents

SELECTIVE INHIBITORS FOR CYCLIN-DEPENDENT KINASES

This invention provides a class of compounds which are useful for specifically inhibiting cyclin-dependent kinases. This class of compounds finds use in treating diseases resulting from inappropriate activity of cyclin-dependent kinases, including cancer, viral infections (e.g., HIV) neurodegenerative disorders (e.g. Alzheimer's disease), and cardiovascular disorders (e.g. atherosclerosis). Moreover, certain members of this class are particularly useful for inhibiting cyclin-dependent kinase 7 and are especially useful for the treatment of breast cancer.

Enzymatic selective transformations of diethyl fumarate

Candida antarctica lipase selectively catalyses transformations of diethyl fumarate in organic solvents. A range of nitrogen nucleophiles, including ammonia, can be successfully used in these enzymatic reactions, monoamides and monohydrazides being obtained in high to moderate yields. In contrast, diethyl maleate is not an adequate substrate for this enzyme.

ENANTIOSELECTIVE HYDROLYSIS BY BAKER'S YEAST - II. ESTERS OF N-ACETYL AMINO ACIDS

D-N-Acetyl amino acid esters were obtained via enantioselective hydrolysis of their racemates by use of fermenting yeast.Evidence is given that proteinases are the enzymes involved.