4072-13-3

Basic information

• Product Name: (2-methoxy-5-methylphenyl)(phenyl)methanone
• CAS NO: 4072-13-3
• Molecular Formula: C₁₅H₁₄O₂
• Molecular Weight: 226.2705
• Mol File: 4072-13-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 389.4°C at 760 mmHg
• Flash Point: 179.4°C
• Density: 1.088g/cm³
• Vapor Pressure: 2.86E-06mmHg at 25°C
• Refractive Index: 1.563
• CAS DataBase Reference: (2-methoxy-5-methylphenyl)(phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-methoxy-5-methylphenyl)(phenyl)methanone(4072-13-3)
• EPA Substance Registry System: (2-methoxy-5-methylphenyl)(phenyl)methanone(4072-13-3)

Safety Data

• Hazardous Substances Data: 4072-13-3(Hazardous Substances Data)

Usage

General Description

(2-methoxy-5-methylphenyl)(phenyl)methanone is a chemical compound with a molecular structure consisting of a benzene ring substituted with a methoxy group and a methyl group. The compound also contains a ketone functional group, which is attached to the benzene ring. (2-methoxy-5-methylphenyl)(phenyl)methanone is often used as an intermediate or a building block in organic synthesis, particularly in the production of pharmaceuticals, agrochemicals, and dyes. It may also have potential applications in various research and industrial processes due to its unique structure and reactivity. However, as with any chemical, proper safety protocols should be followed when handling and using this compound to prevent any potential hazards.

Upstream product

• 104-93-8 p-methylanizole 
• 98-88-4 benzoyl chloride 
• 65-85-0 benzoic acid 
• 1470-57-1 2-hydroxy-5-methylbenzophenone 
• 74-88-4 methyl iodide 
• 77-78-1 dimethyl sulfate 
• 614-34-6 p-cresyl benzoate 

Downstream Products

• 389068-20-6 1-methoxy-4-methyl-2-(1-phenyl-vinyl)-benzene 
• 124937-51-5 (R)-(+)-tolterodine 
• 1275593-51-5 (Z)-2-(3-(diisopropylamino)-1-phenylprop-1-enyl)-4-methylphenol 
• 1275593-53-7 N,N-diisopropylamine-3-(2-methoxy-5-methylphenyl)-3-phenylprop-2-en-1-amine 
• 1470-57-1 2-hydroxy-5-methylbenzophenone 
• 33257-85-1 6-methyl-3,4-diphenyl-2H-chromen-2-one 
• 16299-22-2 6-methyl-4-phenylchromen-2-one 
• 77901-46-3 5-(2-Methoxy-5-methyl-phenyl)-5-phenyl-5H-[1,2,3,4]dioxadiazole 
• 1195140-09-0 2-methoxy-5-methylbenzophenone oxime 
• 108437-83-8 2-methoxy-5-methyl-benzophenone-seqcis-oxime 

Relevant articles and documents

Tf2O as a rapid and efficient promoter for the dehydrative Friedel-Crafts acylation of aromatic compounds with carboxylic acids

The Friedel-Crafts acylation of aromatic compounds with carboxylic acids was investigated in the presence of Tf2O. The reaction was carried out efficiently and very rapidly under mild reaction conditions without the need of any catalyst.

METHOD OF OBTAINING TOLTERODINE

The process comprises reacting a compound of formula (II), where R is a hydroxyl protecting group, and the asterisk indicates an asymmetric carbon atom, with diisopropylamine in the presence of a reducing agent; optionally converting the resulting intermediate into a salt and, if so desired, isolating it; removing the hydroxyl protecting group; and if so desired, separating the desired (R) or (S) enantiomer, or the mixture of enantiomers and/or converting the obtained compound into a pharmaceutically acceptable salt thereof. Tolterodine is a muscarinic receptor antagonist useful in treating urinary incontinence and other symptoms of urinary bladder hyperactivity.

Method for producing 3,3-diarylpropylamines

The invention relates to a novel method for producing 3,3-diarylpropylamines of formula (I), wherein A represents a substituted or unsubstituted aryl radical, X represents H, OH or OR3 and Y, R1, R2 and R3 have