4072-13-3

Usage

Uses

Used in Pharmaceutical Industry:
(2-methoxy-5-methylphenyl)(phenyl)methanone is used as an intermediate or building block in the synthesis of various pharmaceuticals. Its unique structure and reactivity make it a valuable component in the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical sector, (2-methoxy-5-methylphenyl)(phenyl)methanone serves as a key intermediate in the production of agrochemicals. Its properties allow for the creation of effective compounds used in agriculture.
Used in Dye Industry:
(2-methoxy-5-methylphenyl)(phenyl)methanone is utilized as a precursor in the synthesis of dyes. Its molecular structure contributes to the color and properties of the resulting dyes, making it an important component in this industry.
Used in Research and Industrial Processes:
Due to its unique structure and reactivity, (2-methoxy-5-methylphenyl)(phenyl)methanone has potential applications in various research and industrial processes. It can be employed in the development of new materials and chemical reactions.
It is important to follow proper safety protocols when handling and using (2-methoxy-5-methylphenyl)(phenyl)methanone to prevent any potential hazards.

Upstream product

• 104-93-8 p-methylanizole 
• 98-88-4 benzoyl chloride 
• 1470-57-1 2-hydroxy-5-methylbenzophenone 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 
• 614-34-6 p-cresyl benzoate 
• 65-85-0 benzoic acid 

Downstream Products

• 108437-83-8 2-methoxy-5-methyl-benzophenone-seqcis-oxime 
• 1195140-09-0 2-methoxy-5-methylbenzophenone oxime 
• 389068-20-6 1-methoxy-4-methyl-2-(1-phenyl-vinyl)-benzene 
• 1470-57-1 2-hydroxy-5-methylbenzophenone 
• 1275593-53-7 N,N-diisopropylamine-3-(2-methoxy-5-methylphenyl)-3-phenylprop-2-en-1-amine 
• 1275593-51-5 (Z)-2-(3-(diisopropylamino)-1-phenylprop-1-enyl)-4-methylphenol 
• 124937-51-5 (R)-(+)-tolterodine 
• 33257-85-1 6-methyl-3,4-diphenyl-2H-chromen-2-one 
• 16299-22-2 6-methyl-4-phenylchromen-2-one 
• 77901-46-3 5-(2-Methoxy-5-methyl-phenyl)-5-phenyl-5H-[1,2,3,4]dioxadiazole 

Relevant academic research and scientific papers

Tf2O as a rapid and efficient promoter for the dehydrative Friedel-Crafts acylation of aromatic compounds with carboxylic acids

The Friedel-Crafts acylation of aromatic compounds with carboxylic acids was investigated in the presence of Tf2O. The reaction was carried out efficiently and very rapidly under mild reaction conditions without the need of any catalyst.

NOVEL PROCESS FOR THE PREPARATION OF TOLTERODINE

The present invention relates to a novel and improved process for the preparation of tolterodine of formula I. Key steps involved in the process are a vinyl Grignard reaction on a benzophenone derivative of formula XXI to get the vinyl carbinol derivative

METHOD OF OBTAINING TOLTERODINE

The process comprises reacting a compound of formula (II), where R is a hydroxyl protecting group, and the asterisk indicates an asymmetric carbon atom, with diisopropylamine in the presence of a reducing agent; optionally converting the resulting intermediate into a salt and, if so desired, isolating it; removing the hydroxyl protecting group; and if so desired, separating the desired (R) or (S) enantiomer, or the mixture of enantiomers and/or converting the obtained compound into a pharmaceutically acceptable salt thereof. Tolterodine is a muscarinic receptor antagonist useful in treating urinary incontinence and other symptoms of urinary bladder hyperactivity.

Method for producing 3,3-diarylpropylamines

The invention relates to a novel method for producing 3,3-diarylpropylamines of formula (I), wherein A represents a substituted or unsubstituted aryl radical, X represents H, OH or OR3 and Y, R1, R2 and R3 have

Aluminum dodecatungstophosphate (AlPW12O40) as a non-hygroscopic Lewis acid catalyst for the efficient Friedel-Crafts acylation of aromatic compounds under solvent-less conditions

Stable and non-hygroscopic aluminum dodecatungstophosphate (AlPW 12O40), which is prepared easily from cheap and commercially available compounds was found to be an effective catalyst for Friedel-Crafts acylation reactions using carboxylic acids, acetic anhydride and benzoyl chloride in the absence of solvent under mild reaction conditions.

Solvent-free Friedel-Crafts acylation of aromatic compounds with carboxylic acids in the presence of trifluoroacetic anhydride and aluminum dodecatungstophosphate

The stable and non-hygroscopic aluminum dodecatungstophosphate (AlPW12O40), was found to be an effective catalyst (3 mol%) for the solvent-free Friedel-Crafts acylation of aromatic compounds with carboxylic acids in the presence of trifluoroacetic anhydride under mild reaction conditions.